Related references
Note: Only part of the references are listed.Analysis of necroptotic proteins in failing human hearts
Adrian Szobi et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2017)
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
Yingying Zhang et al.
NATURE COMMUNICATIONS (2017)
Cardioprotective Role of Tumor Necrosis Factor Receptor-Associated Factor 2 by Suppressing Apoptosis and Necroptosis
Xiaoyun Guo et al.
CIRCULATION (2017)
ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
Yi-Nan Gong et al.
CELL (2017)
The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873
K. Wang et al.
CELL DEATH AND DIFFERENTIATION (2016)
Necroptotic cell death in failing heart: relevance and proposed mechanisms
Adriana Adameova et al.
HEART FAILURE REVIEWS (2016)
RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation
Juan Lin et al.
NATURE (2016)
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
Jinho Seo et al.
NATURE CELL BIOLOGY (2016)
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis
Ting Zhang et al.
NATURE MEDICINE (2016)
Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectors
C. K. Yang et al.
CELL DEATH & DISEASE (2016)
Hsp90 modulates the stability of MLKL and is required for TNF-induced necroptosis
X. M. Zhao et al.
CELL DEATH & DISEASE (2016)
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death
A. V. Jacobsen et al.
CELL DEATH & DISEASE (2016)
Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis
Dianrong Li et al.
CELL CHEMICAL BIOLOGY (2016)
RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice
Zhe Huang et al.
CELL HOST & MICROBE (2015)
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3
Wanze Chen et al.
NATURE CELL BIOLOGY (2015)
HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart
Chi Keung Lam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis
Dianrong Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Regulation of tumour necrosis factor signalling: live or let die
Dirk Brenner et al.
NATURE REVIEWS IMMUNOLOGY (2015)
RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
Mark Luedde et al.
CARDIOVASCULAR RESEARCH (2014)
Transforming Growth Factor β-Activated Kinase 1 Signaling Pathway Critically Regulates Myocardial Survival and Remodeling
Lei Li et al.
CIRCULATION (2014)
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
Huayi Wang et al.
MOLECULAR CELL (2014)
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
Xiaqiong Wang et al.
NATURE IMMUNOLOGY (2014)
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
Xing Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
Q. Remijsen et al.
CELL DEATH & DISEASE (2014)
Necroptosis induced by RIPK3 requires MLKL but not Drp1
D. M. Moujalled et al.
CELL DEATH & DISEASE (2014)
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
Yves Dondelinger et al.
CELL REPORTS (2014)
Therapeutic Potential of Tumour Necrosis Factor-alpha Antagonists in Patients with Chronic Heart Failure
Qamar Javed et al.
HEART LUNG AND CIRCULATION (2013)
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
James M. Murphy et al.
IMMUNITY (2013)
Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
William J. Kaiser et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Derek J. Hausenloy et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
Andreas Linkermann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases
Roshan J. Thapa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
miR-874 regulates myocardial necrosis by targeting caspase-8
K. Wang et al.
CELL DEATH & DISEASE (2013)
Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis
Stephen W. G. Tait et al.
CELL REPORTS (2013)
Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
Jason Karch et al.
ELIFE (2013)
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo
Martinus I. F. J. Oerlemans et al.
BASIC RESEARCH IN CARDIOLOGY (2012)
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale et al.
CELL (2012)
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
Liming Sun et al.
CELL (2012)
p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
Angelina V. Vaseva et al.
CELL (2012)
The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways
Zhigao Wang et al.
CELL (2012)
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
Jason W. Upton et al.
CELL HOST & MICROBE (2012)
Bax regulates primary necrosis through mitochondrial dynamics
Russell S. Whelan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
N. Vanlangenakker et al.
CELL DEATH AND DIFFERENTIATION (2011)
Programmed Necrosis, Not Apoptosis, in the Heart
Gloria Kung et al.
CIRCULATION RESEARCH (2011)
MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1
Jia Liu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
Angela V. Hafner et al.
AGING-US (2010)
Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance
Russell S. Whelan et al.
ANNUAL REVIEW OF PHYSIOLOGY (2010)
Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
Kerstin Boengler et al.
BASIC RESEARCH IN CARDIOLOGY (2010)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
RIP Kinases at the Crossroads of Cell Death and Survival
Wim Declercq et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
Duan-Wu Zhang et al.
SCIENCE (2009)
Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease
Prabhakar Singh et al.
BIOINFORMATION (2009)
Identification of RIP1 kinase as a specific cellular target of necrostatins
Alexei Degterev et al.
NATURE CHEMICAL BIOLOGY (2008)
Effect of cyclosporine on reperfusion injury in acute myocardial infarction
Christophe Piot et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
The cardioprotective effect of necrostatin requires the cyclophilin-d component of the mitochondrial permeability transition pore
S. Y. Lim et al.
CARDIOVASCULAR DRUGS AND THERAPY (2007)
Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure
Hiroyuki Nakayama et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Necrostatin: A potentially novel cardioprotective agent?
Christopher C. T. Smith et al.
CARDIOVASCULAR DRUGS AND THERAPY (2007)
Cell death by necrosis: towards a molecular definition
Pierre Golstein et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding
Colleen Fearns et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
AC Schinzel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
A Degterev et al.
NATURE CHEMICAL BIOLOGY (2005)
Calmodulin kinase II inhibition protects against structural heart disease
R Zhang et al.
NATURE MEDICINE (2005)
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
CP Baines et al.
NATURE (2005)
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
T Nakagawa et al.
NATURE (2005)
Hsp90 and Cdc37 - a chaperone cancer conspiracy
LH Pearl
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
Inflammatory and anti-inflammatory cytokines in chronic heart failure: Potential therapeutic implications
P Aukrust et al.
ANNALS OF MEDICINE (2005)
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation
Y Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury
JD McCully et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury
DJ Hausenloy et al.
CARDIOVASCULAR RESEARCH (2003)
Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A
SJ Clarke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Losing heart: the role of apoptosis in heart disease - a novel therapeutic target?
C Gill et al.
FASEB JOURNAL (2002)
Necrotic cell death in C-elegans requires the function of calreticulin and regulators of Ca2+ release from the endoplasmic reticulum
KL Xu et al.
NEURON (2001)