Journal
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 14, Issue 1, Pages 44-65Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2018.2505
Keywords
Tumor Markers; Immunosensors; Nanomaterials; Detection
Funding
- National Natural Science Foundation of China [61471168, 61571187]
- China Post-doctoral Science Foundation [2016T90403]
- Postdoctoral Science Foundation of Jiangsu Province [1601021A]
- Natural Science Foundation of Hunan Province [2017JJ209, 2016JJ3053]
- Hunan Key Research Project [2017SK2174]
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Nanomaterials have been widely used to immobilize biomolecules, amplify the signals and concentrate the analytes for detection with good properties including large surface area, good adsorption capacity and high surface activity. In recent years, nanomaterials such as carbon nanomaterials, noble metal nanomaterials, polymers, are widely applied to research and develop immunosensors with high sensitivity and selectivity, which monitor the antigen-antibody reaction for the detection of tumor markers. This review provides an introduction of immunosensors and focuses on the design of electrochemical (EC) immunosensors, electrochemical luminscence (ECL) immunosensors and photoelectrochemical (PEC) immunosensors based on nanomaterials in nearly three years.
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