Journal
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 14, Issue 9, Pages 1515-1542Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2018.2614
Keywords
Silver Nanoparticles; Cancer Theranostics; Nanotoxicity; Multifunctional Platforms
Funding
- Guangdong Science and Technology Department [2015A030310487]
- Health Department of Guangdong Province [A2015503]
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Silver nanoparticles (AgNPs) have attracted great attention in cancer theranostics due to their extraordinary physiochemical and biological properties. This review discusses a large number of papers and summarizes the recent applications of AgNPs in cancer theranostics from the following five perspectives: (1) desirable features of AgNPs for theranostic applications, (2) synthesis of AgNPs by physical, chemical, and biological processes, (3) applications of AgNPs in cancer theranostics in vitro, (4) applications of AgNPs in cancer theranostics in vivo, and (5) nanotoxicity of AgNPs. Furthermore, some views are discussed that concern the synthetic challenges, toxicity, and clinical translation of AgNPs and the future development of multifunctional theranostic platforms. Overall, the historical developments and recent applications of AgNPs confirm their important role in the cancer field. It is strongly believed that AgNPs will open a new route toward cancer theranostics in the near future.
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