Journal
JOURNAL OF BIOMECHANICS
Volume 67, Issue -, Pages 91-97Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2017.11.038
Keywords
Muscle physiology; Sarcomere length; Biomechanical modeling; Patellar pain
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Funding
- National Institutes of Health [R24HD050837]
- Department of Veterans Affairs
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The vast majority of musculoskeletal models are not validated against primary experimental data. Conversely, most human experimental measurements are not explained theoretically using models to provide a mechanistic understanding of experimental results. Here we present a study with both primary human data and primary modeling data. Intraoperative sarcomere length was measured on the human vastus lateralis (VL) and vastus medialis (VM) muscles (n = 8) by laser diffraction. These data were compared to a biomechanical model based on muscle architecture and moment arms obtained independently from cadaveric specimens (n = 9). Measured VL sarcomere length ranged from about 3.2 mu m with the knee flexed to 45 degrees to 3.8 mu m with the knee flexed to 90 degrees. These values were remarkably close to theoretical predictions. Measured VM sarcomere length ranged from 3.6 mu m with the knee flexed to 45 degrees to 4.1 mu m with the knee flexed to 90 degrees. These values were dramatically longer than theoretical predictions. Our measured sarcomere length values suggest that human vasti may have differing functions with regard to knee extension and patellar stabilization. This report underscores the importance of validating experimental data to theoretical models and vice versa. Published by Elsevier Ltd.
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