3.8 Article

Central nervous system cryptococcoma in a Ugandan patient with Human Immunodeficiency Virus

Journal

MEDICAL MYCOLOGY CASE REPORTS
Volume 6, Issue -, Pages 10-13

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.mmcr.2014.08.003

Keywords

Ciyptococcus meningitis; Cryptococcoma; Immunosuppressed Host; Central nervous system; Human Immunodeficiency Virus

Funding

  1. National Institute of Neurologic Diseases and Stroke
  2. National Institute of Allergy and Infectious Diseases and Fogarty International Center [RO1NS086312-01, R01A1078934-04, R25TW009345-02]

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Mortality due to AIDS-related Cryptococcal meningitis (CM) is often > 50% in low-middle income countries. Dissemination of CM can result in intracranial mass lesions known as cryptococcoma. Patients who develop cryptococcomas often have worse outcomes when compared to patients with cryptococcosis without cryptococcoma. We describe a cryptococcoma in the central nervous system (CNS) in a Ugandan patient with AIDS, and review the diagnosis and management with special focus on difficulties encountered in low or middle-income countries. (C) 2014 The Authors. International Society fur Human and Animal Mycology. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license

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