4.6 Article

Genetic code expansion and live cell imaging reveal that Thr-308 phosphorylation is irreplaceable and sufficient for Akt1 activity

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes

Michael Ebner et al.

MOLECULAR CELL (2017)

Article Biochemistry & Molecular Biology

Generation of phospho-ubiquitin variants by orthogonal translation reveals codon skipping

Susanna George et al.

FEBS LETTERS (2016)

Article Oncology

Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors

Patricia Mucci LoRusso

JOURNAL OF CLINICAL ONCOLOGY (2016)

Article Cell Biology

Up-Regulation of Voltage Gated K+ Channels Kv1.3 and Kv1.5 by Protein Kinase PKB/Akt

Jamshed Warsi et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Kinase Regulation by Hydrophobic Spine Assembly in Cancer

Jiancheng Hu et al.

MOLECULAR AND CELLULAR BIOLOGY (2015)

Review Medicine, General & Internal

PI3K/AKT signaling pathway and cancer: an updated review

Miriam Martini et al.

ANNALS OF MEDICINE (2014)

Review Pharmacology & Pharmacy

Turning Off AKT: PHLPP as a Drug Target

Alexandra C. Newton et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 54 (2014)

Article Biochemistry & Molecular Biology

Tuning the signalling output of protein kinase C

Corina E. Antal et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2014)

Article Chemistry, Multidisciplinary

A Facile Strategy for Selective Incorporation of Phosphoserine into Histones

Sangsik Lee et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Article Biochemistry & Molecular Biology

Up-Regulation of the Inwardly Rectifying K+ Channel Kir2.1 (KCNJ2) by Protein Kinase B (PKB/Akt) and PIKfyve

Carlos Munoz et al.

JOURNAL OF MEMBRANE BIOLOGY (2013)

Review Biochemical Research Methods

Spatiotemporal Dynamics of Phosphorylation in Lipid Second Messenger Signaling

Corina E. Antal et al.

MOLECULAR & CELLULAR PROTEOMICS (2013)

Article Biochemical Research Methods

Identification and Quantification of AKT Isoforms and Phosphoforms in Breast Cancer Using a Novel Nanofluidic Immunoassay

Demetris C. Iacovides et al.

MOLECULAR & CELLULAR PROTEOMICS (2013)

Article Oncology

Targeting the PI3-Kinase/Akt/mTOR Signaling Pathway

Burhan Hassan et al.

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (2013)

Article Biochemistry & Molecular Biology

Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation

Jon M. Steichen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Biology

Why nature chose phosphate to modify proteins

Tony Hunter

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)

Article Biochemistry & Molecular Biology

A Mechanism for the Evolution of Phosphorylation Sites

Samuel M. Pearlman et al.

Article Multidisciplinary Sciences

Expanding the Genetic Code of Escherichia coli with Phosphoserine

Hee-Sung Park et al.

SCIENCE (2011)

Article Oncology

Phosphorylation of AKT: a Mutational Analysis

Jonathan R. Hart et al.

ONCOTARGET (2011)

Review Cell Biology

Targeting the PI3K signaling pathway in cancer

Kwok-Kin Wong et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)

Article Chemistry, Medicinal

Synthesis and structure based optimization of novel Akt inhibitors

Blaise Lippa et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Review Biochemistry & Molecular Biology

AKT/PKB signaling: Navigating downstream

Brendan D. Manning et al.

Article Biochemistry & Molecular Biology

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

Camilla Hauge et al.

EMBO JOURNAL (2007)

Article Biochemistry & Molecular Biology

Kinetic mechanism of AKT/PKB enzyme family

Xiaoling Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Biochemistry & Molecular Biology

Perturbations of the AKT signaling pathway in human cancer

DA Altomare et al.

ONCOGENE (2005)

Article Pathology

Expression of activated Akt and PTEN in malignant melanomas - Relationship with clinical outcome

A Slipicevic et al.

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2005)

Article Biochemical Research Methods

Expression and purification of active PKB kinase from Escherichia coli

S Klein et al.

PROTEIN EXPRESSION AND PURIFICATION (2005)

Article Biochemistry & Molecular Biology

Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter

MT Kunkel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

DD Sarbassov et al.

SCIENCE (2005)

Article Biochemistry & Molecular Biology

Structure, regulation and function of PKB/AKT - a major therapeutic target

M Hanada et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2004)

Article Biochemistry & Molecular Biology

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

J Yang et al.

NATURE STRUCTURAL BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

MP Scheid et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Toward a PKB inhibitor: Modification of a selective PKA inhibitor by rational design

H Reuveni et al.

BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

A Toker et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)