4.6 Article

Antimicrobial activity of tellurium-loaded polymeric fiber meshes

Journal

JOURNAL OF APPLIED POLYMER SCIENCE
Volume 135, Issue 25, Pages -

Publisher

WILEY
DOI: 10.1002/app.46368

Keywords

biomedical applications; fibers; manufacturing

Funding

  1. UK Engineering and Physical Sciences Research Council [EP/N0342281]
  2. UK Engineering and Physical Sciences Research Council [EP/N0342281]
  3. EPSRC [EP/N034228/1] Funding Source: UKRI

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A series of poly(methyl methacrylate) solutions loaded with varying concentrations of tellurium particles are prepared and processed into continuous and smooth microfiber meshes. Scanning electron microscopy and energy-dispersive X-ray spectroscopy are used to study the morphology and surface elemental composition of the composite fibers. Fiber diameters range between 7 and 14 mu m with surface nanopores on the fibers ranging between 100 and 200nm. Energy-dispersive X-ray spectroscopy confirmed successful incorporation of tellurium particles into the fibers. The concentration of tellurium in the composite significantly influenced fiber diameter, pore size, and morphology. The antibacterial activity of the prepared fibers is tested using Escherichia coli K12. The fibers are incubated in bacterial suspensions for 24h at 37 degrees C and 150rpm. Antibacterial activity is assessed through the colony-counting method and is found to be dose dependent. The fibers with 4 wt % tellurium exhibited the most potent antibacterial properties as a 1.16 log reduction was observed. (c) 2018 The Authors. Journal of Applied Polymer Science Published by Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46368.

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