Chromatic detection of glucose using polymerization of diacetylene vesicle

A polydiacetylene vesicle was used to fabricate glucose sensor, allowing feasible colorimetric detection. The vesicle was formed by sonication of 10,12-pentacosadiynoic acid (PCDA). H2O2 formed by the reaction between glucose and glucose oxidase functioned as the initiator for the polymerization of PCDA in the presence of horseradish peroxidase. The solution turned blue after the polymerization of PCDA vesicle. Thus, the glucose concentration could be detected to the concentration level that turns the solution to blue. The ultraviolet absorbance of glucose solution was proportional to glucose concentration. The results of this study indicate that glucose concentration upto 1 mM can be detected by change in blue color by eyes. (c) 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46394.