Journal
PSYCHIATRIC CLINICS OF NORTH AMERICA
Volume 37, Issue 3, Pages 337-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.psc.2014.05.004
Keywords
Error monitoring; Conflict monitoring; Response inhibition; Switching; Decision making; Reward; Default mode network; Perseverative cognition
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Cognitive neuroscience investigates neural responses to cognitive and emotional probes, an approach that has yielded critical insights into the neurobiological mechanisms of psychiatric disorders. This article reviews some of the major findings from neuroimaging studies using a cognitive neuroscience approach to investigate obsessive-compulsive disorder (OCD). It evaluates the consistency of results and interprets findings within the context of OCD symptoms, and proposes a model of OCD involving inflexibility of internally focused cognition. Although further research is needed, this body of work probing cognitive-emotional processes in OCD has already shed considerable light on the underlying mechanisms of the disorder.
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