Related references
Note: Only part of the references are listed.Coding Mutations in SORL1 and Alzheimer Disease
Badri N. Vardarajan et al.
ANNALS OF NEUROLOGY (2015)
Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer's Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells
Jessica E. Young et al.
CELL STEM CELL (2015)
No expectation to share incidental findings in genomic research
Anna Middleton et al.
LANCET (2015)
Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study
Elise Cuyvers et al.
LANCET NEUROLOGY (2015)
PLD3 and sporadic Alzheimer's disease risk
Jean-Charles Lambert et al.
NATURE (2015)
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
Stacy Steinberg et al.
NATURE GENETICS (2015)
Population-based Analysis of Alzheimer's Disease Risk Alleles Implicates Genetic Interactions
Mark T. W. Ebbert et al.
BIOLOGICAL PSYCHIATRY (2014)
New applications of disease genetics and pharmacogenetics to drug development
Allen D. Roses et al.
CURRENT OPINION IN PHARMACOLOGY (2014)
Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
L. S. Schneider et al.
JOURNAL OF INTERNAL MEDICINE (2014)
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease
Carlos Cruchaga et al.
NATURE (2014)
Symptom onset in autosomal dominant Alzheimer disease A systematic review and meta-analysis
Davis C. Ryman et al.
NEUROLOGY (2014)
The Evolution of Preclinical Alzheimer's Disease: Implications for Prevention Trials
Reisa Sperling et al.
NEURON (2014)
Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease
Anne M. Fagan et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
The global prevalence of dementia: A systematic review and metaanalysis
Martin Prince et al.
ALZHEIMERS & DEMENTIA (2013)
Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer's disease
E. Rodriguez-Rodriguez et al.
JOURNAL OF NEURAL TRANSMISSION (2013)
CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing
Manasi Malik et al.
JOURNAL OF NEUROSCIENCE (2013)
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
J. Chapuis et al.
MOLECULAR PSYCHIATRY (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
Disease-targeted sequencing: a cornerstone in the clinic
Heidi L. Rehm
NATURE REVIEWS GENETICS (2013)
C9orf72 G4C2 repeat expansions in Alzheimer's disease and mild cognitive impairment
Rita Cacace et al.
NEUROBIOLOGY OF AGING (2013)
Alzheimer's Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Ana Griciuc et al.
NEURON (2013)
ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status
Jared B. Vasquez et al.
NEUROSCIENCE LETTERS (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Genetic susceptibility testing for neurodegenerative diseases: Ethical and practice issues
J. Scott Roberts et al.
PROGRESS IN NEUROBIOLOGY (2013)
Diagnosis and management of Alzheimer's disease: Past, present and future ethical issues
S. Gauthier et al.
PROGRESS IN NEUROBIOLOGY (2013)
Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets
Amy M. Pooler et al.
ALZHEIMERS RESEARCH & THERAPY (2013)
Multilocus genetic profiling to empower drug trials and predict brain atrophy
Omid Kohannim et al.
NEUROIMAGE-CLINICAL (2013)
Locus-specific mutation databases for neurodegenerative brain diseases
Marc Cruts et al.
HUMAN MUTATION (2012)
Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk
Karolien Bettens et al.
MOLECULAR NEURODEGENERATION (2012)
Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites
N. Brouwers et al.
MOLECULAR PSYCHIATRY (2012)
High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease
C. Pottier et al.
MOLECULAR PSYCHIATRY (2012)
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Thorlakur Jonsson et al.
NATURE (2012)
Screening in ALS and FTD patients reveals 3 novel UBQLN2 mutations outside the PXX domain and a pure FTD phenotype
Matthis Synofzik et al.
NEUROBIOLOGY OF AGING (2012)
Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
Alix de Calignon et al.
NEURON (2012)
Expression of Novel Alzheimer's Disease Risk Genes in Control and Alzheimer's Disease Brains
Celeste M. Karch et al.
PLOS ONE (2012)
Genetic counseling and testing for Alzheimer disease: Joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors
Jill S. Goldman et al.
GENETICS IN MEDICINE (2011)
APOE and Alzheimer disease: a major gene with semi-dominant inheritance
E. Genin et al.
MOLECULAR PSYCHIATRY (2011)
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
Adam C. Naj et al.
NATURE GENETICS (2011)
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Paul Hollingworth et al.
NATURE GENETICS (2011)
Alzheimer's risk variants in the clusterin gene are associated with alternative splicing
M. Szymanski et al.
TRANSLATIONAL PSYCHIATRY (2011)
Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2
Suman Jayadev et al.
BRAIN (2010)
Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease
Sudha Seshadri et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
A. D. Roses et al.
PHARMACOGENOMICS JOURNAL (2010)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Denise Harold et al.
NATURE GENETICS (2009)
A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
S. Salloway et al.
NEUROLOGY (2009)
A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
Giuseppe Di Fede et al.
SCIENCE (2009)
Comparing test-specific distress of susceptibility versus deterministic genetic testing for Alzheimer's disease
Michael R. Cassidy et al.
ALZHEIMERS & DEMENTIA (2008)
apoE isoform-specific disruption of amyloid β peptide clearance from mouse brain
Rashid Deane et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family
Nathalie Brouwers et al.
ARCHIVES OF NEUROLOGY (2007)
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
Ekaterina Rogaeva et al.
NATURE GENETICS (2007)
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy
Kristel Sleegers et al.
BRAIN (2006)
Role of genes and environments for explaining Alzheimer disease
M Gatz et al.
ARCHIVES OF GENERAL PSYCHIATRY (2006)
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
A Rovelet-Lecrux et al.
NATURE GENETICS (2006)
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
S Oddo et al.
NEURON (2004)
Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred
P Pastor et al.
ANNALS OF NEUROLOGY (2003)
Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in western Europe
R Rademakers et al.
HUMAN MUTATION (2003)