Journal
GENETICS IN MEDICINE
Volume 18, Issue 5, Pages 501-512Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/gim.2015.118
Keywords
informed decision making; patient education; public education; whole-genome sequencing
Categories
Funding
- Seed Grant Program of the Charles Bronfman Institute for Personalized Medicine
Ask authors/readers for more resources
Background: As whole-genome sequencing (WGS) increases in availability, WGS educational aids are needed for research participants, patients, and the general public. Our aim was therefore to develop an accessible and scalable WGS educational aid. Methods: We engaged multiple stakeholders in an iterative process over a 1-year period culminating in the production of a novel 10-minute WGS educational animated video, Whole Genome Sequencing and You (https://goo.gl/HV8ezJ). We then presented the animated video to 281 online-survey respondents (the video-information group). There were also two comparison groups: a written-information group (n = 281) and a no-information group (n = 300). Results: In the video-information group, 79% reported the video was easy to understand, satisfaction scores were high (mean 4.00 on 1-5 scale, where 5 = high satisfaction), and knowledge increased significantly. There were significant differences in knowledge compared with the no-information group but few differences compared with the written-information group. Intention to receive personal results from WGS and decisional conflict in response to a hypothetical scenario did not differ between the three groups. Conclusions: The educational animated video, Whole Genome Sequencing and You, was well received by this sample of online-survey respondents. Further work is needed to evaluate its utility as an aid to informed decision making about WGS in other populations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available