Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 62, Issue 2, Pages 549-559Publisher
IOS PRESS
DOI: 10.3233/JAD-170908
Keywords
Alzheimer's disease; dysbiosis; gut microbiota; metabolic endotoxemia; physiology
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Gut microbiota plays a crucial role in human health and disease. The alterations in the composition of gut microbiota may cause the onset of certain human pathologies. One of these is Alzheimer's disease (AD). High-fat diets, administration of antibiotics, lack of probiotics and/or prebiotics in diet increase the risk of AD. On the other hand, modulation of the composition of gut microbiota may decrease the risk of AD and be able to slow down the progression of AD.
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