4.5 Review

Hypoxia-Induced Signaling Activation in Neurodegenerative Diseases: Targets for New Therapeutic Strategies

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

β-Amyloid Prions and the Pathobiogy of Alzheimer's Disease

Joel C. Watts et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2018)

Article Geriatrics & Gerontology

Old age potentiates cold-induced tau phosphorylation: linking thermoregulatory deficit with Alzheimer's disease

Marine Tournissac et al.

NEUROBIOLOGY OF AGING (2017)

Review Oncology

The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity

Renaud Vatrinet et al.

CANCER & METABOLISM (2017)

Article Cell Biology

Oxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia

Jose Lopez-Barneo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)

Article Biochemistry & Molecular Biology

The epigenetic regulation of HIF-1α by SIRT1 in MPP+ treated SH-SY5Y cells

Su-Yan Dong et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Medicine, Research & Experimental

Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease

Eugenia B. Manukhina et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2016)

Article Biochemistry & Molecular Biology

Mitochondrial retrograde signaling in the Drosophila nervous system and beyond

Olivia F. Duncan et al.

Review Biochemistry & Molecular Biology

The Importance of Thrombin in Cerebral Injury and Disease

Harald Krenzlin et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Cell Biology

Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity

Thomas Kietzmann et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2016)

Article Multidisciplinary Sciences

Mitochondrial retrograde signaling regulates neuronal function

Umut Cagin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Neurosciences

Is Vasomotion in Cerebral Arteries Impaired in Alzheimer's Disease?

Luigi Yuri Di Marco et al.

JOURNAL OF ALZHEIMERS DISEASE (2015)

Article Biochemistry & Molecular Biology

CD36 Upregulation Mediated by Intranasal LV-NRF2 Treatment Mitigates Hypoxia-Induced Progression of Alzheimer's-Like Pathogenesis

Chun-Yan Wang et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Review Oncology

Monocyte Subpopulations in Angiogenesis

Heather J. Dalton et al.

CANCER RESEARCH (2014)

Article Biochemistry & Molecular Biology

An O2-Sensitive Glomus Cell-Stem Cell Synapse Induces Carotid Body Growth in Chronic Hypoxia

Aida Platero-Luengo et al.

Review Neurosciences

Vitamin D as a Potential Therapy in Amyotrophic Lateral Sclerosis

Alexandro Gianforcaro et al.

CNS NEUROSCIENCE & THERAPEUTICS (2014)

Article Neurosciences

Regulation of the VHL/HIF-1 Pathway by DJ-1

Mohammad Parsanejad et al.

JOURNAL OF NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

ATP5H/KCTD2 locus is associated with Alzheimer's disease risk

M. Boada et al.

MOLECULAR PSYCHIATRY (2014)

Article Clinical Neurology

Hypoxia-Induced Tau Phosphorylation and Memory Deficit in Rats

Chang-E. Zhang et al.

NEURODEGENERATIVE DISEASES (2014)

Review Cell Biology

New Insights into the Role of Mitochondrial Dynamics and Autophagy during Oxidative Stress and Aging in the Heart

Yoshiyuki Ikeda et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)

Article Multidisciplinary Sciences

Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours

Cameron E. Snell et al.

PLOS ONE (2014)

Review Biotechnology & Applied Microbiology

Roles of Vascular Endothelial Growth Factor in Amyotrophic Lateral Sclerosis

Ana Catarina Pronto-Laborinho et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Review Genetics & Heredity

Using the zebrafish model for Alzheimer's disease research

Morgan Newman et al.

FRONTIERS IN GENETICS (2014)

Article Pharmacology & Pharmacy

Hypoxia-Inducible Factor-1 (HIF-1): A Potential Target for Intervention in Ocular Neovascular Diseases

Ramya Krishna Vadlapatla et al.

CURRENT DRUG TARGETS (2013)

Review Biochemistry & Molecular Biology

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by antioxidant metal chelators: From ferroptosis to stroke

Rachel E. Speer et al.

FREE RADICAL BIOLOGY AND MEDICINE (2013)

Article Biochemistry & Molecular Biology

Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

Gustavo Basurto-Islas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Hypoxia Increases Aβ-Induced Tau Phosphorylation by Calpain and Promotes Behavioral Consequences in AD Transgenic Mice

Lianbo Gao et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2013)

Article Neurosciences

Dysregulation of Hypoxia-Inducible Factor by Presenilin/γ-Secretase Loss-of-Function Mutations

Muriel R. Kaufmann et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Biochemistry & Molecular Biology

Neuregulin1beta1 Antagonizes Apoptosis Via ErbB4-Dependent Activation of PI3-Kinase/Akt in APP/PS1 Transgenic Mice

Weigang Cui et al.

NEUROCHEMICAL RESEARCH (2013)

Article Multidisciplinary Sciences

Iron Accumulates in Huntington's Disease Neurons: Protection by Deferoxamine

Jianfang Chen et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Cessation of Neoangiogenesis in Alzheimer's Disease Follows Amyloid-beta Immunization

Kaan E. Biron et al.

SCIENTIFIC REPORTS (2013)

Article Geriatrics & Gerontology

Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia

Debjani Tripathy et al.

FRONTIERS IN AGING NEUROSCIENCE (2013)

Review Behavioral Sciences

Roles for HIF-1α in neural stem cell function and the regenerative response to stroke

Lee Anna Cunningham et al.

BEHAVIOURAL BRAIN RESEARCH (2012)

Article Clinical Neurology

Granular Non-Fibrillar Aggregates and Toxicity in Alzheimer's Disease

Nuria Benseny-Cases et al.

CURRENT ALZHEIMER RESEARCH (2012)

Review Neurosciences

A unifying hypothesis on mammalian neural stem cell properties in the adult hippocampus

Michael A. Bonaguidi et al.

CURRENT OPINION IN NEUROBIOLOGY (2012)

Review Biochemistry & Molecular Biology

The updated biology of hypoxia-inducible factor

Samantha N. Greer et al.

EMBO JOURNAL (2012)

Article Psychology, Biological

Cortical sources of EEG rhythms in congestive heart failure and Alzheimer's disease

Fabrizio Vecchio et al.

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY (2012)

Article Biochemistry & Molecular Biology

Effect of Sodium Valproate Administration on Brain Neprilysin Expression and Memory in Rats

Natalia N. Nalivaeva et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2012)

Article Biochemistry & Molecular Biology

An AD-Related Neuroprotector Rescues Transformed Rat Retinal Ganglion Cells from CoCl2-Induced Apoptosis

Jie Men et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2012)

Article Peripheral Vascular Disease

Hypoxia induces angiogenic factors in brain microvascular endothelial cells

J. Luo et al.

MICROVASCULAR RESEARCH (2012)

Article Neurosciences

Aβ42 production in brain capillary endothelial cells after oxygen and glucose deprivation

Alessandra Bulbarelli et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2012)

Review Neurosciences

Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration

Zu-Hang Sheng et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Review Behavioral Sciences

Traumatic brain injury: A risk factor for Alzheimer's disease

Thamil Mani Sivanandam et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2012)

Review Neurosciences

Amyloid-β Production: Major Link Between Oxidative Stress and BACE1

Elena Tamagno et al.

NEUROTOXICITY RESEARCH (2012)

Review Biochemistry & Molecular Biology

Passing the baton: the HIF switch

Mei Yee Koh et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Article Medicine, Research & Experimental

Mitochondrial Biology and Parkinson's Disease

Celine Perier et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Medicine, Research & Experimental

Inflammation in Alzheimer Disease-A Brief Review of the Basic Science and Clinical Literature

Tony Wyss-Coray et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Medicine, Research & Experimental

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

Rawan Tarawneh et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Medicine, Research & Experimental

The role of ceramides in selected brain pathologies: ischemia/hypoxia, Alzheimer disease

Halina Car et al.

POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ (2012)

Article Clinical Neurology

Erythropoietin and amyotrophic lateral sclerosis: Plasma level determination

Rita Carilho et al.

AMYOTROPHIC LATERAL SCLEROSIS (2011)

Review Biochemistry & Molecular Biology

Injury-induced neurogenesis in the mammalian forebrain

Koji Ohira

CELLULAR AND MOLECULAR LIFE SCIENCES (2011)

Article Medicine, General & Internal

Vascular signaling abnormalities in Alzheimer disease

P. GRAMMAS et al.

CLEVELAND CLINIC JOURNAL OF MEDICINE (2011)

Review Biochemistry & Molecular Biology

Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases

Z. Zhang et al.

CURRENT MEDICINAL CHEMISTRY (2011)

Review Neurosciences

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

Berislav V. Zlokovic

NATURE REVIEWS NEUROSCIENCE (2011)

Article Pathology

Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β

Maya A. Koike et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Article Biochemistry & Molecular Biology

Hypoxia and mitochondrial oxidative metabolism

Giancarlo Solaini et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)

Review Anatomy & Morphology

APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis

Leslie Crews et al.

BRAIN STRUCTURE & FUNCTION (2010)

Article Cell Biology

During hypoxia, HUMMR joins the mitochondrial dance

Yan Li et al.

CELL CYCLE (2010)

Article Neurosciences

Autophagy in the Central Nervous System: Implications for Neurodegenerative Disorders

Maria Xilouri et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2010)

Article Biochemistry & Molecular Biology

Lutein Protects RGC-5 Cells Against Hypoxia and Oxidative Stress

Suk-Yee Li et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2010)

Review Critical Care Medicine

Molecular Mediators of Angiogenesis

Areck A. Ucuzian et al.

JOURNAL OF BURN CARE & RESEARCH (2010)

Article Biochemistry & Molecular Biology

HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells

Jens Leander Johansen et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Review Biochemistry & Molecular Biology

Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration?

Sonia C. Correia et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Article Cell Biology

O2 regulates stem cells through Wnt/β-catenin signalling

Jolly Mazumdar et al.

NATURE CELL BIOLOGY (2010)

Article Neurosciences

Acute hypoxia promote the phosphorylation of tau via ERK pathway

Hui Fang et al.

NEUROSCIENCE LETTERS (2010)

Review Cell Biology

Control of mitochondrial transport and localization in neurons

Andrew F. MacAskill et al.

TRENDS IN CELL BIOLOGY (2010)

Article Medicine, Research & Experimental

Hypoxia and Neurodegeneration

Chris Peers et al.

HYPOXIA AND CONSEQUENCES FROM MOLECULE TO MALADY (2009)

Review Biochemistry & Molecular Biology

Autophagy in neurodegeneration: two sides of the same coin

Jin-A Lee

BMB REPORTS (2009)

Article Biochemistry & Molecular Biology

The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility

Xinnan Wang et al.

Article Biochemistry & Molecular Biology

Angiogenin protects motoneurons against hypoxic injury

J. Sebastia et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Biochemistry & Molecular Biology

Breathing at high altitude

Vincent Joseph et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2009)

Article Clinical Neurology

Hypoxia-inducible factor-1α has a key role in hypoxic preconditioning

Satoshi Taie et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2009)

Article Clinical Neurology

Evidence of angiogenic vessels in Alzheimer's disease

Brinda S. Desai et al.

JOURNAL OF NEURAL TRANSMISSION (2009)

Article Neurosciences

HIF Prolyl Hydroxylase Inhibition Augments Dopamine Release in the Rat Brain In Vivo

Louise Witten et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2009)

Article Biochemistry & Molecular Biology

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

Gregory Bellot et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Hypoxia-Inducible Factor 2 Regulates Hepatic Lipid Metabolism

Erinn B. Rankin et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Biochemistry & Molecular Biology

The Role of Amyloid Precursor Protein Processing by BACE1, the β-Secretase, in Alzheimer Disease Pathophysiology

Sarah L. Cole et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

Huafeng Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Medicine, Research & Experimental

Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart

Nilufer Nermin Turan et al.

LIFE SCIENCES (2008)

Article Physiology

Transcriptional responses to intermittent hypoxia

Jayasri Nanduri et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2008)

Review Oncology

Hypoxia, HIF1 and glucose metabolism in the solid tumour

Nicholas C. Denko

NATURE REVIEWS CANCER (2008)

Article Oncology

Role of erythropoietin in the brain

Constance Tom Noguchi et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2007)

Article Biochemistry & Molecular Biology

Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body

Ricardo Pardal et al.

Article Endocrinology & Metabolism

Erythropoietin-induced neurovascular protection, angiogenesis, and cerebral blood flow restoration after focal ischemia in mice

Ying Li et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)

Article Cell Biology

Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia

Abderrahmane Kaidi et al.

NATURE CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

Xiulian Sun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Pharmacology & Pharmacy

Hypoxia-inducible factor-1 (HIF-1)

Qingdong Ke et al.

MOLECULAR PHARMACOLOGY (2006)

Article Neurosciences

Mitochondrial trafficking to synapses in cultured primary cortical neurons

Diane T. W. Chang et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Cell Biology

Hypoxia requires Notch signaling to maintain the undifferentiated cell state

MV Gustafsson et al.

DEVELOPMENTAL CELL (2005)

Review Biochemistry & Molecular Biology

VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection

E Storkebaum et al.

BIOESSAYS (2004)

Article Biochemistry & Molecular Biology

Physiological levels of amyloid peptides stimulate the angiogenic response through FGF-2

S Cantara et al.

FASEB JOURNAL (2004)

Review Pharmacology & Pharmacy

Modulating the hypoxia-inducible factor signaling pathway: Applications from cardiovascular disease to cancer

KS Hewitson et al.

CURRENT PHARMACEUTICAL DESIGN (2004)

Review Neurosciences

HIf1 and oxygen sensing in the brain

FR Sharp et al.

NATURE REVIEWS NEUROSCIENCE (2004)

Article Medicine, General & Internal

Alzheimer's disease and angiogenesis

AH Vagnucci et al.

LANCET (2003)

Article Multidisciplinary Sciences

Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

KL Jin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Pharmacology & Pharmacy

Signal transduction to hypoxia-inducible factor 1

GL Semenza

BIOCHEMICAL PHARMACOLOGY (2002)

Article Clinical Neurology

Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes, microglia, and oligodendrocytes grown in culture

A Nagai et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)