4.5 Review

Alzheimer's Amyloid-beta is an Antimicrobial Peptide: A Review of the Evidence

Related references

Note: Only part of the references are listed.
Review Endocrinology & Metabolism

Age-associated physiological and pathological changes at the blood-brain barrier: A review

Franciska Erdo et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)

Article Neurosciences

Safety and Efficacy of Anti-Amyloid-β Immunotherapy in Alzheimer's Disease: A Systematic Review and Meta-Analysis

Ross Penninkilampi et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2017)

Review Public, Environmental & Occupational Health

Is Periodontal Disease Associated with Alzheimer's Disease? A Systematic Review with Meta-Analysis

Yago Leira et al.

NEUROEPIDEMIOLOGY (2017)

Article Multidisciplinary Sciences

Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism

Jitka Petrlova et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration

Qingqing Chai et al.

NATURE COMMUNICATIONS (2017)

Article Geriatrics & Gerontology

16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain

David C. Emery et al.

FRONTIERS IN AGING NEUROSCIENCE (2017)

Article Neurosciences

Infection and Alzheimer's Disease: The APOE ε4 Connection and Lipid Metabolism

Nadezda Urosevic et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Article Multidisciplinary Sciences

Polymicrobial Infections In Brain Tissue From Alzheimer's Disease Patients

Diana Pisa et al.

SCIENTIFIC REPORTS (2017)

Article Geriatrics & Gerontology

Periodontitis induced by bacterial infection exacerbates features of Alzheimer's disease in transgenic mice

Naoyuki Ishida et al.

NPJ AGING AND MECHANISMS OF DISEASE (2017)

Article Immunology

NET amyloidogenic backbone in human activated neutrophils

L. Pulze et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2016)

Review Microbiology

Infection in an aging population

Kimberly A. Kline et al.

CURRENT OPINION IN MICROBIOLOGY (2016)

Review Neurosciences

Anti-Viral Properties of Amyloid-beta Peptides

Karine Bourgade et al.

JOURNAL OF ALZHEIMERS DISEASE (2016)

Editorial Material Neurosciences

Microbes and Alzheimer's Disease

Ruth F. Itzhaki et al.

JOURNAL OF ALZHEIMERS DISEASE (2016)

Article Biochemistry & Molecular Biology

Cell Adhesion on Amyloid Fibrils Lacking Integrin Recognition Motif

Reeba S. Jacob et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Cell Biology

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease

Deepak Kumar Vijaya Kumar et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

Amyloid-like ribbons of amelogenins in enamel mineralization

Karina M. M. Carneiro et al.

SCIENTIFIC REPORTS (2016)

Review Geriatrics & Gerontology

Genes associated with Alzheimer's disease: an overview and current status

Mohan Giri et al.

CLINICAL INTERVENTIONS IN AGING (2016)

Article Multidisciplinary Sciences

Amyloidogenic amyloid-β-peptide variants induce microbial agglutination and exert antimicrobial activity

Philipp Spitzer et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

Amyloids: from Pathogenesis to Function

A. A. Nizhnikov et al.

BIOCHEMISTRY-MOSCOW (2015)

Review Clinical Neurology

Clearance systems in the brain-implications for Alzheimer disease

Jenna M. Tarasoff-Conway et al.

NATURE REVIEWS NEUROLOGY (2015)

Article Geriatrics & Gerontology

Herpes simplex virus type 2 infection induces AD-like neurodegeneration markers in human neuroblastoma cells

Henrike Kristen et al.

NEUROBIOLOGY OF AGING (2015)

Review Geriatrics & Gerontology

Historic evidence to support a causal relationship between spirochetal infections and Alzheimer's disease

Judith Miklossy

FRONTIERS IN AGING NEUROSCIENCE (2015)

Article Clinical Neurology

A study on the association between infectious burden and Alzheimer's disease

X. -L. Bu et al.

EUROPEAN JOURNAL OF NEUROLOGY (2015)

Article Multidisciplinary Sciences

Different Brain Regions are Infected with Fungi in Alzheimer's Disease

Diana Pisa et al.

SCIENTIFIC REPORTS (2015)

Article Neurosciences

Herpes Viruses Increase the Risk of Alzheimer's Disease: A Meta-Analysis

Ariah J. Steel et al.

JOURNAL OF ALZHEIMERS DISEASE (2015)

Article Neurosciences

Cerebrospinal Fluid from Alzheimer's Disease Patients Contains Fungal Proteins and DNA

Ruth Alonso et al.

JOURNAL OF ALZHEIMERS DISEASE (2015)

Article Medicine, General & Internal

Safety profile of semagacestat, a gamma-secretase inhibitor: IDENTITY trial findings

David B. Henley et al.

CURRENT MEDICAL RESEARCH AND OPINION (2014)

Article Medicine, General & Internal

Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014

L. S. Schneider et al.

JOURNAL OF INTERNAL MEDICINE (2014)

Article Biotechnology & Applied Microbiology

Origins of amyloid-β

William G. Tharp et al.

BMC GENOMICS (2013)

Review Geriatrics & Gerontology

Expression and function of APP and its metabolites outside the central nervous system

Kendra L. Puig et al.

EXPERIMENTAL GERONTOLOGY (2013)

Article Geriatrics & Gerontology

A multicenter, blinded, randomized, factorial controlled trial of doxycycline and rifampin for treatment of Alzheimer's disease: the DARAD trial

D. William Molloy et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2013)

Article Clinical Neurology

Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections

Jan Jessen Krut et al.

JOURNAL OF NEUROLOGY (2013)

Article Medicine, General & Internal

A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease

Rachelle S. Doody et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Neurosciences

β-Secretase Cleavage of the Fly Amyloid Precursor Protein Is Required for Glial Survival

Bonnie J. Bolkan et al.

JOURNAL OF NEUROSCIENCE (2012)

Review Medicine, Research & Experimental

Antimicrobial Properties of Amyloid Peptides

Bruce L. Kagan et al.

MOLECULAR PHARMACEUTICS (2012)

Article Medicine, Research & Experimental

Fluid Biomarkers in Alzheimer Disease

Kaj Blennow et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Biochemistry & Molecular Biology

Testing the Therapeutic Potential of Doxycycline in a Drosophila melanogaster Model of Alzheimer Disease

Rita Costa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Geriatrics & Gerontology

HSV-1 promotes Ca2+-mediated APP phosphorylation and Aβ accumulation in rat cortical neurons

Roberto Piacentini et al.

NEUROBIOLOGY OF AGING (2011)

Article Microbiology

Statins Enhance Formation of Phagocyte Extracellular Traps

Ohn A. Chow et al.

CELL HOST & MICROBE (2010)

Article Behavioral Sciences

Five-year Survival After Helicobacter pylori Eradication in Alzheimer Disease Patients

Jannis Kountouras et al.

COGNITIVE AND BEHAVIORAL NEUROLOGY (2010)

Review Pharmacology & Pharmacy

Neurotoxicity of beta-Amyloid Protein: Oligomerization, Channel Formation and Calcium Dyshomeostasis

Masahiro Kawahara

CURRENT PHARMACEUTICAL DESIGN (2010)

Article Multidisciplinary Sciences

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

Stephanie J. Soscia et al.

PLOS ONE (2010)

Article Clinical Neurology

Amyloid and tau cerebrospinal fluid biomarkers in HIV infection

Magnus Gisslen et al.

BMC NEUROLOGY (2009)

Article Medicine, General & Internal

Effect of Tarenflurbil on Cognitive Decline and Activities of Daily Living in Patients With Mild Alzheimer Disease A Randomized Controlled Trial

Robert C. Green et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Article Biochemistry & Molecular Biology

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

Robert W. Mahley et al.

JOURNAL OF LIPID RESEARCH (2009)

Review Genetics & Heredity

Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps

Maren von Kockritz-Blickwede et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2009)

Review Neurosciences

HIV Regulation of Amyloid Beta Production

Lynn Pulliam

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2009)

Review Biochemistry & Molecular Biology

Amyloid Precursor Protein Trafficking, Processing, and Function

Gopal Thinakaran et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

Shida Yousefi et al.

NATURE MEDICINE (2008)

Article Neurosciences

Tat peptides inhibit neprilysin

Abigail Daily et al.

JOURNAL OF NEUROVIROLOGY (2006)

Article Geriatrics & Gerontology

Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes

J Miklossy et al.

NEUROBIOLOGY OF AGING (2006)

Article Immunology

The receptor-binding region of human apolipoprotein E has direct anti-infective activity

CB Dobson et al.

JOURNAL OF INFECTIOUS DISEASES (2006)

Article Medicine, Research & Experimental

Plaques of Alzheimer's disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete

Alan B. MacDonald

MEDICAL HYPOTHESES (2006)

Article Microbiology

Herpes simplex virus interferes with amyloid precursor protein processing

SJ Shipley et al.

BMC MICROBIOLOGY (2005)

Article Immunology

HIV-1 Tat inhibits neprilysin and elevates amyloid β

HC Rempel et al.

Article Geriatrics & Gerontology

Chlamydia pneumoniae induces Alzheimer-like amyloid plaques in brains of BALB/c mice

CS Little et al.

NEUROBIOLOGY OF AGING (2004)

Article Geriatrics & Gerontology

Lessons from the AN 1792 Alzheimer vaccine:: lest we forget

SR Robinson et al.

NEUROBIOLOGY OF AGING (2004)

Article Geriatrics & Gerontology

Challenges and directions for the pathogen hypothesis of Alzheimer's disease

SR Robinson et al.

NEUROBIOLOGY OF AGING (2004)

Review Biochemistry & Molecular Biology

What the evolution of the amyloid protein precursor supergene family tells us about its function

EJ Coulson et al.

NEUROCHEMISTRY INTERNATIONAL (2000)