Related references
Note: Only part of the references are listed.An In Vivo 11C-(R)-PK11195 PET and In Vitro Pathology Study of Microglia Activation in Creutzfeldt-Jakob Disease
Leonardo Iaccarino et al.
MOLECULAR NEUROBIOLOGY (2018)
Genomic variants, genes, and pathways of Alzheimer's disease: An overview
Adam C. Naj et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2017)
Extended and direct evaluation of RT-QuIC assays for Creutzfeldt-Jakob disease diagnosis
Bradley R. Groveman et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2017)
BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis
Shuting Zhang et al.
JOURNAL OF NEUROSCIENCE (2017)
Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples
Matilde Bongianni et al.
JAMA NEUROLOGY (2017)
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia
Veronica Redaelli et al.
SCIENTIFIC REPORTS (2017)
The A2V mutation as a new tool for hindering Aβ aggregation: A neutron and x-ray diffraction study
Laura Cantu et al.
SCIENTIFIC REPORTS (2017)
Pathogenic Aβ A2V versus protective Aβ A2T mutation: Early stage aggregation and membrane interaction
Laura Colombo et al.
BIOPHYSICAL CHEMISTRY (2017)
Drug candidates in clinical trials for Alzheimer's disease
Shih-Ya Hung et al.
JOURNAL OF BIOMEDICAL SCIENCE (2017)
Advanced tests for early and accurate diagnosis of Creutzfeldt-Jakob disease
Gianluigi Zanusso et al.
NATURE REVIEWS NEUROLOGY (2016)
Novel PSEN1 mutations (H214N and R220P) associated with familial Alzheimer's disease identified by targeted exome sequencing
Elena Piccoli et al.
NEUROBIOLOGY OF AGING (2016)
The new β amyloid-derived peptide Aβ1-6A2V-TAT(D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity
Luisa Diomede et al.
NEUROBIOLOGY OF DISEASE (2016)
The cell-permeable Aβ1-6A2VTAT(D) peptide reverts synaptopathy induced by Aβ1-42wt
Sara Cimini et al.
NEUROBIOLOGY OF DISEASE (2016)
Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease
Luis Concha-Marambio et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β
Giuseppe Di Fede et al.
SCIENTIFIC REPORTS (2016)
Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways
C. Bohm et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2015)
Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases
Gianluigi Forloni et al.
PRION (2015)
Additional mechanisms conferring genetic susceptibility to Alzheimer's disease
Miguel Calero et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers
Christiane Reitz et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Panencephalopathic Creutzfeldt-Jakob Disease with Distinct Pattern of Prion Protein Deposition in a Patient with D178N Mutation and Homozygosity for Valine at Codon 129 of the Prion Protein Gene
Gabriella Marcon et al.
BRAIN PATHOLOGY (2014)
The Peculiar Role of the A2V Mutation in Amyloid-β (Aβ) 1-42 Molecular Assembly
Massimo Messa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation
Iryna Benilova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity
Yuichi Hashimoto et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial
Stephane Haik et al.
LANCET NEUROLOGY (2014)
Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity
Luisa Diomede et al.
NEUROBIOLOGY OF DISEASE (2014)
Prions in the Urine of Patients with Variant Creutzfeldt- Jakob Disease
Fabio Moda et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Preclinical Detection of Variant CJD and BSE Prions in Blood
Caroline Lacroux et al.
PLOS PATHOGENS (2014)
Clinical Genetics of Alzheimer's Disease
Zhangyu Zou et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Therapy in Prion Diseases
Gianluigi Forloni et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Hereditary and sporadic beta-amyloidoses
Giuseppe Di Fede et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2013)
Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population
Mia Kero et al.
NEUROBIOLOGY OF AGING (2013)
Early Detection of Abnormal Prion Protein in Genetic Human Prion Diseases Now Possible Using Real-Time QUIC Assay
Kazunori Sano et al.
PLOS ONE (2013)
HIV-1 Tat Interacts with and Regulates the Localization and Processing of Amyloid Precursor Protein
Jiyoung Kim et al.
PLOS ONE (2013)
The immunobiology of prion diseases
Adriano Aguzzi et al.
NATURE REVIEWS IMMUNOLOGY (2013)
APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38
Maria Luisa Moro et al.
ACTA NEUROPATHOLOGICA (2012)
Oral biodrug delivery using cell-penetrating peptide
El-Sayed Khafagy et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
Sporadic human prion diseases: molecular insights and diagnosis
Gianfranco Puoti et al.
LANCET NEUROLOGY (2012)
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Thorlakur Jonsson et al.
NATURE (2012)
INTRANASAL ADMINISTRATION OF TAT-haFGF14-154 ATTENUATES DISEASE PROGRESSION IN A MOUSE MODEL OF ALZHEIMER'S DISEASE
G. Lou et al.
NEUROSCIENCE (2012)
Good gene, bad gene: New APP variant may be both
Giuseppe Di Fede et al.
PROGRESS IN NEUROBIOLOGY (2012)
Molecular biology and pathology of prion strains in sporadic human prion diseases
Pierluigi Gambetti et al.
ACTA NEUROPATHOLOGICA (2011)
Brain Oligomeric β-Amyloid but Not Total Amyloid Plaque Burden Correlates With Neuronal Loss and Astrocyte Inflammatory Response in Amyloid Precursor Protein/Tau Transgenic Mice
Bibiana DaRocha-Souto et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Ultra-Efficient PrPSc Amplification Highlights Potentialities and Pitfalls of PMCA Technology
Gian Mario Cosseddu et al.
PLOS PATHOGENS (2011)
Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features
Giorgio Giaccone et al.
ACTA NEUROPATHOLOGICA (2010)
Hereditary Cerebral Hemorrhage With Amyloidosis Associated With the E693K Mutation of APP
Orso Bugiani et al.
ARCHIVES OF NEUROLOGY (2010)
Alzheimer's Aβ Peptides with Disease-Associated N-Terminal Modifications: Influence of Isomerisation, Truncation and Mutation on Cu2+ Coordination
Simon C. Drew et al.
PLOS ONE (2010)
Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics
Ignazio Cali et al.
BRAIN (2009)
A Novel Italian Presenilin 2 Gene Mutation with Prevalent Behavioral Phenotype
Gabriella Marcon et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Creutzfeldt-Jakob disease with E200K PRNP mutation: a case report and revision of the literature
Michelangelo Mancuso et al.
NEUROLOGICAL SCIENCES (2009)
A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
Giuseppe Di Fede et al.
SCIENCE (2009)
S3-01-03: Prion therapy: Tetracyclic compounds in animal models and patients with Creutzfeldt-Jakob disease
Fabrizio Tagliavini
Alzheimers & Dementia (2008)
A new amyloid μ variant favoring oligomerization in Alzheimer's-type dementia
Takami Tomiyama et al.
ANNALS OF NEUROLOGY (2008)
The anti-fibrillogenic activity of tetracyclines on PrP 106-126:: a 3D-QSAR study
Ugo Cosentino et al.
JOURNAL OF MOLECULAR MODELING (2008)
A novel insertional mutation in the prion protein gene: clinical and bio-molecular findings
C. Mauro et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Atypical presentation of Creutzfeldt-Jakob disease: The first Italian case associated with E196K mutation in the PRNP gene
F. Clerici et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Tauopathy in human and experimental variant Creutzfeldt-Jakob disease
G. Giaccone et al.
NEUROBIOLOGY OF AGING (2008)
Atypical frontotemporal dementia as a new clinical phenotype of Gerstmann-Straussler-Scheinker disease with the PrP-P102L mutation. Description of a previously unreported Italian family
Anna Rita Giovagnoli et al.
NEUROLOGICAL SCIENCES (2008)
A novel PSEN2 mutation associated with a peculiar phenotype
P. Piscopo et al.
NEUROLOGY (2008)
The Efficacy of Tetracyclines in Peripheral and Intracerebral Prion Infection
Ada De Luigi et al.
PLOS ONE (2008)
A versatile prion replication assay in organotypic brain slices
Jeppe Falsig et al.
NATURE NEUROSCIENCE (2008)
A general model of prion strains and their pathogenicity
John Collinge et al.
SCIENCE (2007)
The ε isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Straussler-Scheinker disease
Giuseppe Di Fede et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification
Paula Saa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A weakly clustered n terminus inhibits Aβ(1-40) amyloidogenesis
Kwang Hun Lim
CHEMBIOCHEM (2006)
Pathogenesis of prion diseases: current status and future outlook
Adriano Aguzzi et al.
NATURE REVIEWS MICROBIOLOGY (2006)
Classification of sporadic Creutzfeldt-Jakob disease revisited
Ignazio Cali et al.
BRAIN (2006)
Prion diseases - Current understanding of epidemiology and pathogenesis, and therapeutic advances
M Caramelli et al.
CNS DRUGS (2006)
Cognitive deficits in familial Alzheimer's disease associated with M239V mutation of presenilin 2
Anna Rita Giovagnoli et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2006)
Sporadic Creutzfeldt-Jakob disease:: The extent of microglia activation is dependent on the biochemical type of PrPSc
G Puoti et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Pre-symptomatic detection of prions by cyclic amplification of protein misfolding
C Soto et al.
FEBS LETTERS (2005)
HIV-1 Tat inhibits neprilysin and elevates amyloid β
HC Rempel et al.
AIDS (2005)
Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene
G Marcon et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Mapping Aβ amyloid fibril secondary structure using scanning proline mutagenesis
AD Williams et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene
G Rossi et al.
NEUROLOGY (2004)
The current status of Alzheimer's disease genetics: what do we tell the patients?
L Bertram et al.
PHARMACOLOGICAL RESEARCH (2004)
Creutzfeldt-Jakob disease with a novel extra-repeat insertional mutation in the PRNP gene
V Pietrini et al.
NEUROLOGY (2003)
Emerging therapeutic agents for transmissible spongiform encephalopathies: a review
T Koster et al.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS (2003)
Causative and susceptibility genes for Alzheimer's disease: a review
A Rocchi et al.
BRAIN RESEARCH BULLETIN (2003)
Therapeutic approaches to prion diseases
G Rossi et al.
CLINICS IN LABORATORY MEDICINE (2003)
Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology
F Bard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Acquired prion disease: iatrogenic CJD, variant CJD, kuru
RG Will
BRITISH MEDICAL BULLETIN (2003)
Sporadic and familial CJD: classification and characterisation
P Gambetti et al.
BRITISH MEDICAL BULLETIN (2003)
Tetracyclines affect prion infectivity
G Forloni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Human prion diseases
MS Sy et al.
MEDICAL CLINICS OF NORTH AMERICA (2002)
Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures
M Takao et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation
C Nilsberth et al.
NATURE NEUROSCIENCE (2001)
Pathogenic effects of D23N Iowa mutant amyloid β-protein
WE Van Nostrand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The stimulation of inducible nitric-oxide synthase by the prion protein fragment 106-126 in human microglia is tumor necrosis factor-α-dependent and involves p38 mitogen-activated protein kinase
C Fabrizi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
GP Saborio et al.
NATURE (2001)
A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Straussler-Scheinker disease A117V
F Tagliavini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Anti-amyloidogenic activity of tetracyclines: studies in vitro
G Forloni et al.
FEBS LETTERS (2001)
Creutzfeldt-Jakob disease with a novel four extra-repeat insertional mutation in the PrP gene
G Rossi et al.
NEUROLOGY (2000)
Tetracycline affects abnormal properties of synthetic PrP peptides and PrPSc in vitro
F Tagliavini et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Share Paper
