4.5 Article

Multifactorial Hypothesis and Multi-Targets for Alzheimer's Disease

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

Drugs in Clinical Trials for Alzheimer's Disease: The Major Trends

Sergey O. Bachurin et al.

MEDICINAL RESEARCH REVIEWS (2017)

Review Neurosciences

Revolution of Resting-State Functional Neuroimaging Genetics in Alzheimer's Disease

Patrizia A. Chiesa et al.

TRENDS IN NEUROSCIENCES (2017)

Review Chemistry, Medicinal

Targeting Insulin Signaling for the Treatment of Alzheimer's Disease

Yanxing Chen et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)

Review Clinical Neurology

Tau and neurodegenerative disease: the story so far

Khalid Iqbal et al.

NATURE REVIEWS NEUROLOGY (2016)

Review Clinical Neurology

O-GlcNAcylation: A regulator of tau pathology and neurodegeneration

Cheng-Xin Gong et al.

ALZHEIMERS & DEMENTIA (2016)

Editorial Material Psychiatry

Alzheimer's disease: the amyloid hypothesis on trial

Judith R. Harrison et al.

BRITISH JOURNAL OF PSYCHIATRY (2016)

Review Medicine, Research & Experimental

The amyloid hypothesis of Alzheimer's disease at 25years

Dennis J. Selkoe et al.

EMBO MOLECULAR MEDICINE (2016)

Review Neurosciences

Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

Mercedes Unzeta et al.

FRONTIERS IN NEUROSCIENCE (2016)

Review Neurosciences

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

Rona R. Ramsay et al.

FRONTIERS IN NEUROSCIENCE (2016)

Review Neurosciences

Innate Immunity Fights Alzheimer's Disease

Marie-Victoire Guillot-Sestier et al.

TRENDS IN NEUROSCIENCES (2015)

Review Pharmacology & Pharmacy

Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles

Khalid Iqbal et al.

BIOCHEMICAL PHARMACOLOGY (2014)

Article Biochemistry & Molecular Biology

Recent Development of Multifunctional Agents as Potential Drug Candidates for the Treatment of Alzheimer’s Disease

Natalia Guzior et al.

CURRENT MEDICINAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Dietary Polyphenols for Treatment of Alzheimer's Disease- Future Research and Development

D. Sheeja Malar et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2014)

Review Endocrinology & Metabolism

Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

Christian Hoelscher

JOURNAL OF ENDOCRINOLOGY (2014)

Article Biochemistry & Molecular Biology

8-Hydroxyquinoline Schiff-base compounds as antioxidants and modulators of copper-mediated Aβ peptide aggregation

Luiza M. F. Gomes et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2014)

Review Oncology

Rapid learning for precision oncology

Jeff Shrager et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2014)

Review Chemistry, Medicinal

Dual Inhibitors of beta-Amyloid Aggregation and Acetylcholinesterase as Multi-Target Anti-Alzheimer Drug Candidates

Elisabet Viayna et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)

Review Clinical Neurology

Alzheimer disease therapy-moving from amyloid-β to tau

Ezio Giacobini et al.

NATURE REVIEWS NEUROLOGY (2013)

Review Chemistry, Medicinal

Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

Rafael Leon et al.

MEDICINAL RESEARCH REVIEWS (2013)

Review Chemistry, Medicinal

Drug Repositioning: An Opportunity to Develop Novel Treatments for Alzheimer's Disease

Anne Corbett et al.

PHARMACEUTICALS (2013)

Article Geriatrics & Gerontology

Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice

Simon Gengler et al.

NEUROBIOLOGY OF AGING (2012)

Article Biochemistry & Molecular Biology

Benzenediol-berberine hybrids: Multifunctional agents for Alzheimer's disease

Huailei Jiang et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial

Khalid Iqbal et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2010)

Review Biochemistry & Molecular Biology

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

Paula I. Moreira et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)

Article Biochemistry & Molecular Biology

Dual-target-directed 1,3-diphenylurea derivatives: BACE 1 inhibitor and metal chelator against Alzheimer's disease

Wenhai Huang et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2010)

Review Biochemistry & Molecular Biology

Tacrine Derivatives and Alzheimer's Disease

V. Tumiatti et al.

CURRENT MEDICINAL CHEMISTRY (2010)

Review Neurosciences

The Alzheimer's Disease Mitochondrial Cascade Hypothesis

Russell H. Swerdlow et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Chemistry, Medicinal

Design, Synthesis, and Biological Evaluation of a Novel Class of γ-Secretase Modulators with PPARγ Activity

Martina Hieke et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Chemistry, Medicinal

Bivalent β-Carbolines as Potential Multitarget Anti-Alzheimer Agents

Yvonne Rook et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and β-secretase

Yiping Zhu et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2009)

Review Biochemistry & Molecular Biology

Insulin resistance and Alzheimer's disease

Suzanne M. de la Monte

BMB REPORTS (2009)

Article Biochemistry & Molecular Biology

New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties

Rafael Leon et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2008)

Article Chemistry, Medicinal

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds

Lorna Piazzi et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Review Behavioral Sciences

Clinical Trial Design Issues in Mild to Moderate Alzheimer Disease

David S. Knopman

COGNITIVE AND BEHAVIORAL NEUROLOGY (2008)

Article Clinical Neurology

Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers

K Iqbal et al.

ANNALS OF NEUROLOGY (2005)

Review Clinical Neurology

Metabolic/signal transduction hypothesis of Alzheime's disease and other tauopathies

K Iqbal et al.

ACTA NEUROPATHOLOGICA (2005)

Review Clinical Neurology

Alzheimer's disease: the two-hit hypothesis

XW Zhu et al.

LANCET NEUROLOGY (2004)