4.5 Review

Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer's Disease

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Mitochondria as a target for neuroprotection: implications for Alzheimer's disease

Susana Cardoso et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2017)

Review Clinical Neurology

Mitochondria as a target for neuroprotection: implications for Alzheimer's disease

Susana Cardoso et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2017)

Review Neurosciences

Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease

Qian Cai et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Review Neurosciences

Mitochondrial Permeability Transition Pore as a Suitable Target for Neuroprotective Agents Against Alzheimer's Disease

Elena F. Shevtsova et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2017)

Review Geriatrics & Gerontology

Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease

Amandine Grimm et al.

BIOGERONTOLOGY (2016)

Article Geriatrics & Gerontology

EGb761 improves cognitive function and regulates inflammatory responses in the APP/PS1 mouse

Wenbin Wan et al.

EXPERIMENTAL GERONTOLOGY (2016)

Article Behavioral Sciences

Alzheimer, mitochondria and gender

Amandine Grimm et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2016)

Review Geriatrics & Gerontology

Mitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based Therapies

Isaac G. Onyango et al.

AGING AND DISEASE (2016)

Article Neurosciences

A Mitochondrial Role of SV2a Protein in Aging and Alzheimer's Disease: Studies with Levetiracetam

Carola Stockburger et al.

JOURNAL OF ALZHEIMERS DISEASE (2016)

Article Medicine, General & Internal

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

Gerwyn Morris et al.

BMC MEDICINE (2015)

Article Neurosciences

Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine)

Aleksey Ustyugov et al.

MOLECULAR NEUROBIOLOGY (2015)

Article Neurosciences

The case for rejecting the amyloid cascade hypothesis

Karl Herrup

NATURE NEUROSCIENCE (2015)

Review Behavioral Sciences

Synapses, spines and kinases in mammalian learning and memory, and the impact of aging

Eddy A. van der Zee

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2015)

Article Pharmacology & Pharmacy

Procognitive Compounds Promote Neurite Outgrowth

Matthew Page et al.

PHARMACOLOGY (2015)

Article Neurosciences

Rice Bran Extract Compensates Mitochondrial Dysfunction in a Cellular Model of Early Alzheimer's Disease

Stephanie Hagl et al.

JOURNAL OF ALZHEIMERS DISEASE (2015)

Review Clinical Neurology

Targeting the Prodromal Stage of Alzheimer's Disease: Bioenergetic and Mitochondrial Opportunities

Charles C. Caldwell et al.

NEUROTHERAPEUTICS (2015)

Review Cell Biology

On the origin of Alzheimer's disease. Trials and tribulations of the amyloid hypothesis

Michael A. Castello et al.

AGEING RESEARCH REVIEWS (2014)

Review Pharmacology & Pharmacy

Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles

Khalid Iqbal et al.

BIOCHEMICAL PHARMACOLOGY (2014)

Review Biochemistry & Molecular Biology

The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

Russell H. Swerdlow et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Review Biochemistry & Molecular Biology

Mitochondrial permeability transition pore is a potential drug target for neurodegeneration

Valasani Koteswara Rao et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Article Clinical Neurology

Dimebon Attenuates the A beta-Induced Mitochondrial Permeabilization

Elena F. Shevtsova et al.

CURRENT ALZHEIMER RESEARCH (2014)

Article Neurosciences

A Cell Model for the Initial Phase of Sporadic Alzheimer's Disease

Carola Stockburger et al.

JOURNAL OF ALZHEIMERS DISEASE (2014)

Review Cell Biology

Mitochondrial Dysfunction: Different Routes to Alzheimer's Disease Therapy

Pasquale Picone et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)

Article Chemistry, Medicinal

Protective effect and mechanism of Ginkgo biloba extract-EGb 761 on STZ-induced diabetic cardiomyopathy in rats

Arminder Singh Saini et al.

PHARMACOGNOSY MAGAZINE (2014)

Article Medicine, Research & Experimental

Effect of piracetam on the cognitive performance of patients undergoing coronary bypass surgery: A meta-analysis

Yu Fang et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2014)

Article Biochemistry & Molecular Biology

Improvement of mitochondrial function and dynamics by the metabolic enhancer piracetam

Carola Stockburger et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2013)

Article Pharmacology & Pharmacy

Key Role of Mitochondria in Alzheimer's Disease Synaptic Dysfunction

Virve Cavallucci et al.

CURRENT PHARMACEUTICAL DESIGN (2013)

Article Neurosciences

Reduced VDAC1 Protects Against Alzheimer's Disease, Mitochondria, and Synaptic Deficiencies

Maria Manczak et al.

JOURNAL OF ALZHEIMERS DISEASE (2013)

Article Biochemistry & Molecular Biology

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model

J. W. Steele et al.

MOLECULAR PSYCHIATRY (2013)

Review Biotechnology & Applied Microbiology

Pharmacological approaches to restore mitochondrial function

Penelope A. Andreux et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Review Neurosciences

SYNAPTIC CHANGES IN ALZHEIMER'S DISEASE AND ITS MODELS

J. Pozueta et al.

NEUROSCIENCE (2013)

Article Geriatrics & Gerontology

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)

Shannon L. Risacher et al.

FRONTIERS IN AGING NEUROSCIENCE (2013)

Review Cardiac & Cardiovascular Systems

Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion

Kyriakos N. Papanicolaou et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)

Review Biochemistry & Molecular Biology

Synaptic Mitochondrial Pathology in Alzheimer's Disease

Heng Du et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Article Biochemistry & Molecular Biology

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

Kristina Leuner et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Article Cardiac & Cardiovascular Systems

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

Jerome Piquereau et al.

CARDIOVASCULAR RESEARCH (2012)

Article Psychology, Clinical

Effects of the standardized Ginkgo biloba extract EGb 761® on neuroplasticity

Walter E. Mueller et al.

INTERNATIONAL PSYCHOGERIATRICS (2012)

Article Neurosciences

Dimebon Ameliorates Amyloid-β Induced Impairments of Mitochondrial Form and Function

Schamim H. Eckert et al.

JOURNAL OF ALZHEIMERS DISEASE (2012)

Review Cell Biology

VDAC, a multi-functional mitochondrial protein as a pharmacological target

Varda Shoshan-Barmatz et al.

MITOCHONDRION (2012)

Article Neurosciences

Effects of Polyphenols on Brain Ageing and Alzheimer's Disease: Focus on Mitochondria

Sebastian Schaffer et al.

MOLECULAR NEUROBIOLOGY (2012)

Article Geriatrics & Gerontology

Impairments of Synaptic Plasticity in Aged Animals and in Animal Models of Alzheimer's Disease

Marta Balietti et al.

REJUVENATION RESEARCH (2012)

Review Neurosciences

Synapses and Dendritic Spines as Pathogenic Targets in Alzheimer's Disease

Wendou Yu et al.

NEURAL PLASTICITY (2012)

Review Neurosciences

Spines, Plasticity, and Cognition in Alzheimer's Model Mice

Tara Spires-Jones et al.

NEURAL PLASTICITY (2012)

Article Pharmacology & Pharmacy

The acute effects of dimebolin, a potential Alzheimer's disease treatment, on working memory in rhesus monkeys

Scott J. Webster et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Review Neurosciences

Dimebolin in Dementia

Deepak Sachdeva et al.

CNS NEUROSCIENCE & THERAPEUTICS (2011)

Review Clinical Neurology

Dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice

Julie Vignisse et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2011)

Review Neurosciences

Mitochondria and neuroplasticity

Aiwu Cheng et al.

ASN NEURO (2010)

Article Biochemistry & Molecular Biology

Discovery of a Proneurogenic, Neuroprotective Chemical

Andrew A. Pieper et al.

Review Neurosciences

A Synergistic Dysfunction of Mitochondrial Fission/Fusion Dynamics and Mitophagy in Alzheimer's Disease

Renato X. Santos et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Neurosciences

Dimebon (Latrepirdine) Enhances Mitochondrial Function and Protects Neuronal Cells from Death

Shouting Zhang et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Review Neurosciences

The Alzheimer's Disease Mitochondrial Cascade Hypothesis

Russell H. Swerdlow et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Editorial Material Cell Biology

New insights into the role of mitochondria in aging: mitochondrial dynamics and more

Arnold Y. Seo et al.

JOURNAL OF CELL SCIENCE (2010)

Review Cardiac & Cardiovascular Systems

Regulation and pharmacology of the mitochondrial permeability transition pore

Dmitry B. Zorov et al.

CARDIOVASCULAR RESEARCH (2009)

Review Neurosciences

Pharmacological inhibition of mitochondrial membrane permeabilization for neuroprotection

Toshio Hisatomi et al.

EXPERIMENTAL NEUROLOGY (2009)

Article Chemistry, Medicinal

Nootropic agents stimulate neurogenesis Brain Cells, Inc.: WO2007104035

Philippe Thupin

EXPERT OPINION ON THERAPEUTIC PATENTS (2009)

Article Neurosciences

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

Xinglong Wang et al.

JOURNAL OF NEUROSCIENCE (2009)

Review Biochemistry & Molecular Biology

Ultrastructure of the mitochondrion and its bearing on function and bioenergetics

Giovanni Benard et al.

ANTIOXIDANTS & REDOX SIGNALING (2008)

Review Behavioral Sciences

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

Dennis J. Selkoe

BEHAVIOURAL BRAIN RESEARCH (2008)

Review Neurosciences

Mitochondria in Neuroplasticity and Neurological Disorders

Mark P. Mattson et al.

NEURON (2008)

Article Cell Biology

Piracetam improves cognitive deficits caused by chronic cerebral hypoperfusion in rats

Zhi He et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2008)

Article Pharmacology & Pharmacy

Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761)

Reham Abdel-Kader et al.

PHARMACOLOGICAL RESEARCH (2007)

Review Biochemistry & Molecular Biology

Mitochondrial dysfunction in aging and Alzheimer's disease: Strategies to protect neurons

P. Hemachandra Reddy

ANTIOXIDANTS & REDOX SIGNALING (2007)

Review Biochemistry & Molecular Biology

Mitochondrial dysfunction:: The first domino in brain aging and Alzheimer's disease?

Kristina Leuner et al.

ANTIOXIDANTS & REDOX SIGNALING (2007)

Review Biochemistry & Molecular Biology

Intersection between mitochondrial permeability pores and mitochondrial fusion/fission

Irina G. Gazaryan et al.

NEUROCHEMICAL RESEARCH (2007)

Article Pharmacology & Pharmacy

Piracetam improves mitochondrial dysfunction following oxidative stress

U Keil et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Review Neurosciences

Neural plasticity in the ageing brain

SN Burke et al.

NATURE REVIEWS NEUROSCIENCE (2006)

Review Medicine, Research & Experimental

A mitochondrial cascade hypthesis for sporadic Alzheimer's disease

RH Swerdlow et al.

MEDICAL HYPOTHESES (2004)

Article Multidisciplinary Sciences

Inhibition of amyloid-β aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761

Y Luo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Geriatrics & Gerontology

Clinical efficacy of piracetam in cognitive impairment: A meta-analysis

T Waegemans et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2002)

Article Neurosciences

The ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β-amyloid

S Bastianetto et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2000)

Article Medicine, Research & Experimental

Dimebon improves learning in animals with experimental Alzheimer's disease

NN Lermontova et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2000)