Journal
WORLD JOURNAL OF HEPATOLOGY
Volume 6, Issue 10, Pages 745-751Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4254/wjh.v6.i10.745
Keywords
Complication; Liver failure; Bile leakage; Renal failure; Ascites; Coagulation disorder; Surgical site infection
Categories
Funding
- Ministry of Education, Culture, Sports, Science, and Technology [26461921, 26461920, 25861207]
- Grants-in-Aid for Scientific Research [26461920, 26461921, 25861207, 24390304] Funding Source: KAKEN
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Liver resection is the gold standard treatment for certain liver tumors such as hepatocellular carcinoma and metastatic liver tumors. Some patients with such tumors already have reduced liver function due to chronic hepatitis, liver cirrhosis, or chemotherapy-associated steatohepatitis before surgery. Therefore, complications due to poor liver function are inevitable after liver resection. Although the mortality rate of liver resection has been reduced to a few percent in recent case series, its overall morbidity rate is reported to range from 4.1% to 47.7%. The large degree of variation in the post-liver resection morbidity rates reported in previous studies might be due to the lack of consensus regarding the definitions and classification of post-liver resection complications. The Clavien-Dindo (CD) classification of post-operative complications is widely accepted internationally. However, it is hard to apply to some major post-liver resection complications because the consensus definitions and grading systems for post-hepatectomy liver failure and bile leakage established by the International Study Group of Liver Surgery are incompatible with the CD classification. Therefore, a unified classification of post-liver resection complications has to be established to allow comparisons between academic reports. (c) 2014 Baishideng Publishing Group Inc. All rights reserved.
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