Journal
DIAGNOSIS
Volume 1, Issue 4, Pages 305-309Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/dx-2014-0055
Keywords
gold nanoparticles; molecular diagnostics; nanodiagnostics; nanotechnology; point-of-care
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Funding
- Fundacao para a Cincia e a Tecnologia [PEst-OE/SAU/UI0009/2011-14]
- Fundação para a Ciência e a Tecnologia [PEst-OE/SAU/UI0009/2011] Funding Source: FCT
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Nanotechnology has provided a plethora of valuable tools that can be applied for the detection of biomolecules and analytes relevant for diagnosis purposes nanodiagnostics. This surging new field of molecular diagnostics has been revolutionizing laboratory procedures and providing new ways to assess disease biomarkers with increased sensitivity. While most of the reported nanodiagnostics systems are proof-of-concepts that demonstrate their efficacy in the lab, several nanodiagnostics platforms have already matured to a level that open the way for effective translation to the clinics. Nanodiagnostics platforms (e.g., gold nanoparticles containing systems) have been remarkably useful for the development of molecular diagnosis strategies for DNA/RNA detection and characterization, including systems suitable for point-of-care. How near are nanodiagnostics to go from the bench to the bedside?
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