Radiation Dose-Volume Effects for Liver SBRT

Stereotactic body radiation therapy (SBRT) has emerged as an effective, noninvasive treatment option for primary liver cancer and metastatic disease occurring in the liver. Although SBRT can be highly effective for establishing local control in hepatic malignancies, a tradeoff exists between tumor control and normal tissue complications. The objective of the present study was to review the normal tissue dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and derive normal tissue complication probability models. ? 2018 Elsevier Inc. All rights reserved.

Automated summary

SBRT is an effective, noninvasive treatment option for primary liver cancer and metastatic disease in the liver, although there is a tradeoff between tumor control and normal tissue complications. This study aimed to review the dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and develop normal tissue complication probability models.