Journal
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
Volume 47, Issue 11, Pages 1465-1473Publisher
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.ijom.2018.06.011
Keywords
guided bone regeneration; socket preservation; dimensional change; keratinized tissue; non-resorbable membrane
Categories
Ask authors/readers for more resources
The aim of this randomized clinical trial was to evaluate the newly formed tissues in post-extraction sockets and to compare ridge dimensional changes with and without the use of a dense polytetrafluoroethylene membrane (d-PTFE). Twenty human extraction sockets (lower molars and premolars) received either an intentionally exposed d-PTFE membrane (test group) or no biomaterial (control group). After 4 months, during preparation for implant placement, bone and gingival tissues were collected for histological and biomolecular analysis. Clinically, the test and control groups showed mean gains of keratinized gingiva of 4.30 +/- 1.20 mm and 2.50 +/- 2.20 mm, respectively. A reduction in ridge width was observed in the control (2.90 +/- 2.70 mm) and test (3.30 +/- 2.00 mm) groups. The bone height alteration ranged from a reduction of 0.12 +/- 1.60 mm to a gain of 0.60 + 3.60 mm on average for both groups. Analysis of gene expression (OPG/RANKL) in gingival fibroblasts and osteoblasts revealed no difference between the two groups. Ridge preservation using the d-PTFE membrane increased the formation of keratinized tissue. A reduction in width and mild reduction/gain in height of the alveolar ridge was observed in both groups. The membrane had no influence on the healing process.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available