Journal
AIDS AND BEHAVIOR
Volume 18, Issue 12, Pages 2265-2273Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10461-014-0916-7
Keywords
Adherence; Pill counts; Antiretroviral therapy
Funding
- NIAAA NIH HHS [U01 AA020793, U24 AA020801, U01AA020793] Funding Source: Medline
- NIAID NIH HHS [P30 AI027757, R24 AI067039] Funding Source: Medline
- NIAMS NIH HHS [U01 AR057954, U01 AR057954-S1] Funding Source: Medline
- NIMH NIH HHS [R01 MH084759] Funding Source: Medline
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Phone-based unannounced pill counts to measure medication adherence are much more practical and less expensive than home-based unannounced pill counts, but their validity has not been widely assessed. We examined the validity of phone versus home-based pill counts using a simplified protocol streamlined for studies embedded in clinical care settings. A total of 100 paired counts were used to compare concordance between unannounced phone and home-based pill counts using interclass correlations. Discrepancy analyses using chi(2) tests compared demographic and clinical characteristics across patients who were concordant between phone and home-based pill counts and patients who were not concordant. Concordance was high for phone-based and home-based unannounced total pill counts, as well as individual medication counts and calculated adherence. This study demonstrates that a simplified phone-based pill count protocol can be implemented among patients from a routine clinical care setting and is a feasible means of monitoring medication adherence.
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