Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/ijms19020444
Keywords
silver ions; silver nanoparticles; silver nanocompounds; nanotechnology; mode of action; resistance of bacteria
Funding
- National Science Centre [2017/01/X/NZ1/00765]
- Ministry of Science and High Education [0420/1396/16]
- Wrocaw Centre of Biotechnology, program The Leading National Research Centre (KNOW, Krajowy Narodowy Orodek Wiodcy)
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Silver is considered as antibacterial agent with well-known mode of action and bacterial resistance against it is well described. The development of nanotechnology provided different methods for the modification of the chemical and physical structure of silver, which may increase its antibacterial potential. The physico-chemical properties of silver nanoparticles and their interaction with living cells differs substantially from those of silver ions. Moreover, the variety of the forms and characteristics of various silver nanoparticles are also responsible for differences in their antibacterial mode of action and probably bacterial mechanism of resistance. The paper discusses in details the aforementioned aspects of silver activity.
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