4.7 Review

EP4 as a Therapeutic Target for Aggressive Human Breast Cancer

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

COX-2 induces oncogenic micro RNA miR655 in human breast cancer

Mousumi Majumder et al.

SCIENTIFIC REPORTS (2018)

Article Cell Biology

EP4 receptor promotes invadopodia and invasion in human breast cancer

Felix Tonisen et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2017)

Review Oncology

Immunotherapy in Breast Cancer: the Emerging Role of PD-1 and PD-L1

Francois Bertucci et al.

CURRENT ONCOLOGY REPORTS (2017)

Review Pharmacology & Pharmacy

Structural features of subtype-selective EP receptor modulators

Tijana Markovic et al.

DRUG DISCOVERY TODAY (2017)

Article Chemistry, Medicinal

Discovery of AAT-008, a novel, potent, and selective prostaglandin EP4 receptor antagonist

Yoshiyuki Okumura et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Biochemistry & Molecular Biology

Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation

Iuliia Filipenko et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2016)

Review Pharmacology & Pharmacy

The Roles of EP4 Prostanoid Receptors in Cancer Malignancy Signaling

Hiromichi Fujino

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2016)

Review Oncology

G protein-coupled receptors as promising cancer targets

Ying Liu et al.

CANCER LETTERS (2016)

Article Cell & Tissue Engineering

COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis

Mousumi Majumder et al.

STEM CELLS (2016)

Review Pharmacology & Pharmacy

Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?

G. O'Callaghan et al.

BRITISH JOURNAL OF PHARMACOLOGY (2015)

Article Oncology

COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation

Mousumi Majumder et al.

MOLECULAR CANCER RESEARCH (2015)

Review Oncology

Antagonists of PD-1 and PD-L1 in Cancer Treatment

Evan J. Lipson et al.

SEMINARS IN ONCOLOGY (2015)

Article Oncology

Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties

Namita Kundu et al.

BREAST CANCER RESEARCH AND TREATMENT (2014)

Article Biochemistry & Molecular Biology

An EP4 Antagonist ONO-AE3-208 Suppresses Cell Invasion, Migration, and Metastasis of Prostate Cancer

Song Xu et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2014)

Article Oncology

Cyclooxygenase-2 expression in non-metastatic triple-negative breast cancer patients

Kailash Mosalpuria et al.

MOLECULAR AND CLINICAL ONCOLOGY (2014)

Review Pharmacology & Pharmacy

E-type prostanoid receptor 4 (EP4) in disease and therapy

Viktoria Konya et al.

PHARMACOLOGY & THERAPEUTICS (2013)

Review Cell & Tissue Engineering

Cancer Stem Cells: Current Status and Evolving Complexities

Jane E. Visvader et al.

CELL STEM CELL (2012)

Review Oncology

Personalized Medicine in Breast Cancer: A Systematic Review

Sang-Hoon Cho et al.

JOURNAL OF BREAST CANCER (2012)

Review Oncology

Prostaglandin E2 EP receptors as therapeutic targets in breast cancer

Jocelyn Reader et al.

CANCER AND METASTASIS REVIEWS (2011)

Review Oncology

The role of the EP receptors for prostaglandin E2 in skin and skin cancer

J. E. Rundhaug et al.

CANCER AND METASTASIS REVIEWS (2011)

Review Biotechnology & Applied Microbiology

G protein-coupled receptors: novel targets for drug discovery in cancer

Rosamaria Lappano et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Surgery

Circulating microRNAs as Novel Minimally Invasive Biomarkers for Breast Cancer

Helen M. Heneghan et al.

ANNALS OF SURGERY (2010)

Article Gastroenterology & Hepatology

Aberrant crypt foci: are they intermediate endpoints of colon carcinogenesis in humans?

Akshay K. Gupta et al.

CURRENT OPINION IN GASTROENTEROLOGY (2009)

Article Oncology

Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications

Steven G. Gray et al.

EUROPEAN JOURNAL OF CANCER (2009)

Article Biochemistry & Molecular Biology

Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells

Mei-Ren Pan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Pharmacology & Pharmacy

Cyclooxygenase-2-linked attenuation of hypoxia-induced pulmonary hypertension and intravascular thrombosis

Mary-Clare Cathcart et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Article Oncology

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

Xiaoxian Li et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)

Review Biochemistry & Molecular Biology

Roles of eicosanoids in prostate cancer

Kasem Nithipatikom et al.

FUTURE LIPIDOLOGY (2008)

Review Biochemistry & Molecular Biology

Prostaglandin E receptors

Yukihiko Sugimoto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Oncology

MicroRNA signatures in human cancers

George A. Calin et al.

NATURE REVIEWS CANCER (2006)

Article Medicine, General & Internal

Concordance among gene-expression-based predictors for breast cancer

Cheng Fan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Oncology

COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer

AV Timoshenko et al.

BRITISH JOURNAL OF CANCER (2006)

Review Oncology

Oncomirs - microRNAs with a role in cancer

A Esquela-Kerscher et al.

NATURE REVIEWS CANCER (2006)

Review Oncology

Cancer stem cells: An old idea - A paradigm shift

MS Wicha et al.

CANCER RESEARCH (2006)

Review Oncology

COX inhibitors and breast cancer

D Mazhar et al.

BRITISH JOURNAL OF CANCER (2006)

Article Multidisciplinary Sciences

Role of β-arrestin 1 in the metastatic progression of colorectal cancer

FG Buchanan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Pharmacology & Pharmacy

Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition

DL Simmons et al.

PHARMACOLOGICAL REVIEWS (2004)

Article Oncology

Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells

AV Timoshenko et al.

EXPERIMENTAL CELL RESEARCH (2003)

Article Cell Biology

Prostaglandin E2 modulates dendritic cell function via EP2 and EP4 receptor subtypes

H Harizi et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2003)

Article Multidisciplinary Sciences

Prospective identification of tumorigenic breast cancer cells

M Al-Hajj et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Oncology

COX-2 inhibitors for the prevention of breast cancer

LR Howe et al.

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2003)

Article Biochemistry & Molecular Biology

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

CH Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Review Pharmacology & Pharmacy

Prostanoid receptors: Subtypes and signaling

RM Breyer et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)