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K Huang et al.
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Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2) - A reassessment using novel receptor-specific vascular endothelial growth factor mutants
H Gille et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans
A Sawano et al.
BLOOD (2001)
Angiogenesis in cancer and other diseases
P Carmeliet et al.
NATURE (2000)
Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells
N Rahimi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)