Journal
GENERAL HOSPITAL PSYCHIATRY
Volume 37, Issue 6, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.genhosppsych.2015.07.002
Keywords
Multiple Sclerosis; Manic state; Psychosis; Orbitofrontal; Corticosteroids
Categories
Ask authors/readers for more resources
Several studies have reported a higher prevalence of unipolar depression and bipolar disorder among patients with multiple sclerosis (MS). However, only a few studies have reported manic episodes concomitant with new lesions enhanced by gadolinium on brain magnetic resonance imaging (MRI). Here we report the case of a 47-year-old woman suffering from MS admitted for a manic episode with psychotic features. Brain MRI revealed three new T2 lesions enhanced by gadolinium located in the corpus callosum and in ventromedial prefrontal regions. She rapidly recovered with intravenous methylprednisolone in combination with risperidone. In conclusion, in this patient, the fact that gadolinium-enhancing lesion coincided with new symptoms which responded quickly to corticosteroids suggests that the manic episode was an acute manifestation of MS. (c) 2015 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available