Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 7, Issue 50, Pages 27755-27764Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsami.5b08765
Keywords
microwave heating; gold nanoparticles; poly(N-isopropylacrylamide); concanavalin A; controlled display
Funding
- Wound Management Innovation Co-operative Research Centre
- Alexander von Humboldt Foundation
Ask authors/readers for more resources
We demonstrate microwave-induced heating of gold nanoparticles and nanorods. An appreciably higher and concentration-dependent microwave-induced heating rate was observed with aqueous dispersions of the nanomaterials as opposed to pure water and other controls. Grafted with the thermoresponsive polymer poly(N-isopropylacrylamide), these gold nanomaterials react to microwave-induced heating with a conformational change in the polymer shell, leading to particle aggregation. We subsequently covalently immobilize concanavalin A (Con A) on the thermoresponsive gold nanoparticles. Con A is a bioreceptor commonly used in bacterial sensors because of its affinity for carbohydrates on bacterial cell surfaces. The microwave-induced thermal transitions of the polymer reversibly switch on and off the display of Con A on the particle surface and hence the interactions of the nanomaterials with carbohydrate-functionalized surfaces. This effect was determined using linear sweep voltammetry on a methyl-alpha-D-mannopyranoside-functionalized electrode.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available