3.8 Proceedings Paper

Hypocholesterolemic and Hypoglycemic Effect of Cowpea (Vigna unguiculata L. Walp) Incorporated Experimental Diets in Wistar Rats (Rattus norvegicus)

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.aaspro.2014.11.056

Keywords

Cowpea; wistar rats; cholesterol; hypolipidemic effect; hypoglycemic effect

Funding

  1. Institute of Fundamental Studies, Kandy, Faculty of Agriculture
  2. University of Peradeniya and National Science Foundation [RG/2011/AG/09]

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This study was carried out to investigate the hypocholesterolemic and hypoglycemic effect of four cowpea cultivars. Wistar rats were grouped and fed a high fat diet with 20% Bombay (BO), 20% MI 35 (MI), 20% Waruni (WA), 20% Dawala (DA) in comparison with 20% casein (HFD). Serum total cholesterol, non-HDL cholesterol, triacylglyceride and glucose concentrations and serum antioxidant activity were analysed. Serum lipids, glucose concentrations and serum antioxidant activity in WA fed rats were significantly lower (P < 0.05) than HFD. Therefore, raw Waruni cowpea produced significant hypolipidemic and hypoglycemic effects in Wistar rats. (C) 2014 Published by Elsevier B.V.

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