Journal
INFLAMMATORY BOWEL DISEASES
Volume 24, Issue 9, Pages 1895-1903Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ibd/izy075
Keywords
inflammatory bowel disease; dysplasia; colorectal cancer; surveillance; endoscopy
Categories
Ask authors/readers for more resources
Colorectal cancer is the most serious complication of chronic inflammatory bowel disease. It is generally accepted that dysplasia in most cases precedes the development of colorectal cancer. Thus, detection of dysplasia through surveillance may allow therapeutic interventions to lower the risk of cancer. Our understanding of dysplasia has evolved over the past decades and guided rational decision-making, but many questions remain unanswered. We are currently at the brink of a new era, where new avenues in the endoscopic detection and management of dysplasia are pursued, and the paradigm of a colectomy being the preferred treatment for advanced neoplasia is changing. This review provides a histopathological characterization of dysplasia and aims at summarizing our current understanding of the disease from a clinical point of view. Management algorithms presented seek to aid clinicians and patients in dealing with dysplasia, and future perspectives are discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available