Journal
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
Volume 57, Issue 31, Pages 10118-10125Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.iecr.8b01655
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Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo - Fapesp [2013/26290-5]
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Despite the broad variety of substrates tested for lactic acid production, most of them have problems, even those with promising results. The use of sugar cane molasses appears as a viable alternative, allowing the development of high-performance lactic acid production with yeast extract. In this study, different strategies are proposed and evaluated to achieve high yield, productivity, and lactic acid concentrations considering the suitable association among strain physiology, osmotic stress, substrates, pH control, and fermentation operational parameters. With these strategies and using molasses as a substrate, it was possible to obtain a yield of 95%, with a productivity of 5.38 g L-1 h(-1), and a titer of 157.95 g/L of lactic acid.
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