Journal
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
Volume 52, Issue 3, Pages 449-455Publisher
ASSOC PHARMACEUTICAL TEACHERS INDIA
DOI: 10.5530/ijper.52.3.52
Keywords
Bio reduction; Copper oxide; Green synthesis; Cuprous oxide; Metallic nanoparticles; Callistemon viminails
Funding
- ICMR (Indian Council for Medical Research), Delhi
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Objectives: Nanoparticles synthesis via green approach is a scorching theme of research nowadays as it minimizes the use of harmful chemicals. Not much work has been done on bio reduction of copper salts; therefore our present work was focused on green synthesis of copper oxide nanoparticles using leaf extract of Callistemon vim/nails. Methods: Bio reduction method was used for preparation of copper oxide nanoparticles using Callistemon vim/nails leaf extract. Synthesis was carried out at three different temperatures namely 4 degrees C, room temperature and 60 degrees C. Results: Completion of reaction occurred at 60 degrees C and reduced copper oxide particles were further characterized by ultra violet spectroscopy, dynamic light scattering technique, fourier transform infrared spectroscopy, X-ray diffraction and photoluminescence spectroscopy. The antibacterial evaluation of nanoparticles was done against standard bacterial strains Acinetobacter baumannii and Escherich/a coll. Synthesized copper oxide nanoparticles were found to exhibit antibacterial activity in both pathogenic strains. Conclusion: Overall we can conclude that bio reduction is facilitated at 60 degrees C and it is rapid, simple, inexpensive and effective way of producing antibacterial copper oxide nanoparticles.
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