4.3 Article

A rare case of unilateral diffuse melanocytic proliferation

Journal

INDIAN JOURNAL OF OPHTHALMOLOGY
Volume 66, Issue 4, Pages 588-590

Publisher

MEDKNOW PUBLICATIONS & MEDIA PVT LTD
DOI: 10.4103/ijo.IJO_979_17

Keywords

Bevacizumab; bilateral diffuse uveal melanocytic proliferation; giraffe pattern; leopard mottling; unilateral diffuse uveal melanocytic proliferation

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A 67-year-old woman presented with metamorphopsia in the right eye. Leopard mottling was seen temporal to the fovea oculus dexter with corresponding hyper- and hypo-autofluorescent lesions on fundus autofluorescence. Spectral domain-optical coherence tomography revealed hyperreflective dots in the retinal pigment epithelium and choroid with subretinal fluid (SRF). Intravitreal bevacizumab was administered with which SRF resolved, albeit with increase in the areas of mottling. The patient was diagnosed to have metastatic ductal carcinoma of the right breast. It is important to bear in mind that the well-known entity of bilateral diffuse uveal melanocytic proliferation can rarely present unilaterally.

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