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Treatment of upper airway resistance syndrome in adults: Where do we stand?

Journal

SLEEP SCIENCE
Volume 8, Issue 1, Pages 42-48

Publisher

BRAZILIAN ASSOC SLEEP
DOI: 10.1016/j.slsci.2015.03.001

Keywords

Upper airway resistance syndrome; flow limitation; Treatment; Arousal; Daytime sleepiness

Funding

  1. Associacao Fundo de Incentivo a Pesquisa (AFIP)
  2. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
  3. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)

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Objective: To evaluate the available literature regarding Upper Airway Resistance Syndrome (UARS) treatment Methods: Keywords Upper Airway Resistance Syndrome, Sleep-related Breathing Disorder treatment, Obstructive Sleep Apnea treatment and flow limitation and sleep were used in main databases. Results: We found 27 articles describing UARS treatment. Nasal continuous positive airway pressure (CPAP) has been the mainstay therapy prescribed but with limited effectiveness. Studies about surgical treatments had methodological limitations. Oral appliances seem to be effective but their efficacy is not yet established. Conclusion: Randomized controlled trials with larger numbers of patients and longterm follow-up are important to establish UARS treatment options. (C) 2015 Brazilian Association of Sleep. Production and Hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license

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