4.7 Review

Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day

Journal

JOURNAL OF EXTRACELLULAR VESICLES
Volume 4, Issue -, Pages -

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3402/jev.v4.26901

Keywords

extracellular vesicles; thrombosis; cancer; tissue factor

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Funding

  1. MRC [MR/J003360/1] Funding Source: UKRI
  2. Medical Research Council [MR/J003360/1] Funding Source: Medline
  3. NCATS NIH HHS [UH2 TR000931, UH3 TR000931] Funding Source: Medline
  4. Medical Research Council [MR/J003360/1] Funding Source: researchfish

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Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor-bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.

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