4.7 Article

WU Polyomavirus in Respiratory Epithelial Cells from Lung Transplant Patient with Job Syndrome

Journal

EMERGING INFECTIOUS DISEASES
Volume 21, Issue 1, Pages 103-106

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid2101.140855

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Funding

  1. National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH [P30AR048335]
  2. Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH [R21AI095922]
  3. Children's Discovery Institute at Washington University in St. Louis
  4. NIH Intramural Research Program
  5. Center for Cancer Research
  6. Department of Defense through the National Defense Science and Engineering Graduate Fellowship Program
  7. National Institute of Allergy and Infectious Diseases

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We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1. Co-staining for an epithelial cell marker identified most WUPyV viral protein 1 positive cells as respiratory epithelial cells.

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