4.7 Article

Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups

Journal

EMERGING INFECTIOUS DISEASES
Volume 21, Issue 2, Pages 312-315

Publisher

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2102.140649

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Funding

  1. Council of the President of the Russian Federation [MK-1843.2013.4]
  2. Russian Academy of Agriculture Science

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African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV's extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.

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