Journal
BIOFABRICATION
Volume 7, Issue 1, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/1758-5090/7/1/015014
Keywords
Fe3O4/sodium lauryl sulfate/antibiotic nanoparticles; core/shell; matrix assisted pulsed laser evaporation; antimicrobial activity
Funding
- Romanian National Authority for Scientific Research [CNCS-UEFISCDI: PN-II-ID-PCE-2011-3-0888 (209/5.10.2011), PN-II-RU-TE-2012-3-0379 (16/2013)]
- Sectorial Operational Programme Human Resources Development
- European Social Fund
- Romanian Government [POSDRU/159/1.5/S/134398]
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We report the fabrication of biofunctionalized magnetite core/sodium lauryl sulfate shell/antibiotic adsorption-shell nanoparticles assembled thin coatings by matrix assisted pulsed laser evaporation for antibacterial drug-targeted delivery. Magnetite nanoparticles have been synthesized and subsequently characterized by transmission electron microscopy and x-ray diffraction. The obtained thin coatings have been investigated by FTIR and scanning electron microscope, and tested by in vitro biological assays, for their influence on in vitro bacterial biofilm development and cytotoxicity on human epidermoid carcinoma (HEp2) cells.
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