Journal
GYNECOLOGICAL ENDOCRINOLOGY
Volume 34, Issue 9, Pages 789-792Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09513590.2018.1459549
Keywords
Polycystic ovary syndrome; laparoscopic ovarian drilling; anti-Mullerian hormone; ovarian reserve; ovarian blood flow
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This prospective cohort study was conducted on 80 patients with clomiphene citrate (CC)-resistant polycystic ovary syndrome undergoing laparoscopic ovarian drilling (LOD). Pre- and post-LOD ovarian reserve parameters (anti-Mullerian hormone: AMH, ovarian volume: OV, and antral follicle count: AFC) and ovarian stromal blood flow indices (Vascularization index: VI, flow index: FI, and vascularization flow index: VFI) were measured to explore the effect of LOD and to find out the correlation between serum AMH and different clinical, hormonal, and ultrasonic variables. There was a highly significant reduction of the serum AMH (p<.001) after LOD with significant reduction in OV, AFC and vascular indices (VI, FI and VFI) of the right and left ovaries (p<.05). LOD significantly reduced ovarian reserve parameters (AMH, OV and AFC) and ovarian stromal blood flow indices (VI, FI and VFI) with no observed correlation between AMH levels and Doppler indices.
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