Journal
ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY
Volume 7, Issue 2, Pages 99-107Publisher
UNIV FEDERAL MATO GROSSO SUL, DEPT QUIMICA
Keywords
lichens; scavenging activity; phenolic compounds; DPPH concentration
Categories
Funding
- Fundacao de Apoio ao Desenvolvimento do Ensino, Ciencia e Tecnologia do Estado de Mato Grosso do Sul (Fundect)
Ask authors/readers for more resources
Lichens produce a wide range of phenolic substances, mostly depsides and depsidones. As part of our ongoing study of lichens from the Cerrado biome in Mato Grosso do Sul state, the present article reports novel findings on the radical-scavenging activity of two depsides, five depsidones, usnic acid, and lichexanthone that were evaluated against 0.1 and 0.3 mM 2,2-diphenyl-1-picrylhydrazyl radical concentrations. These substances were isolated from the lichens Parmotrema tinctorum (Nyl.) Hale, Parmotrema dilatatum (Vain.) Hale, Pseudoparmelia sphaerospora (Nyl.) Hale, Parmotrema lichexanthonicum Eliasaro & Adler, Ramalina anceps Nyl. Usnea subcomosa Vain. and Usnea jamaicensis Ach. Usnic acid (EC50 = 3.34 +/- 1.44 and 5.97 +/- 1.91 mM, respectively) and atranorin (2.48 +/- 1.18 and 10.10 +/- 1.18 mM, respectively) proved the most active unmodified compounds. Lecanoric and protocetraric acids exhibited significant EC50 differences between DPPH concentrations. Besides these, nine 9-O-alkyl protocetraric acid derivatives were also evaluated. 9-O-methyl protocetraric and 9-O-iso-propyl protocetraric acids (with respective EC50 values of 1.74 +/- 0.83 and 1.03 +/- 1.0 mM, both against 0.1 mM DPPH) were the most active compounds evaluated. Except for 9-O-methyl protocetraric acid, chain elongation correlated with increased scavenging activity in the linear series from 9-O-ethyl to 9-O-n-hexyl protocetraric acid.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available