Journal
DRUG DISCOVERIES AND THERAPEUTICS
Volume 9, Issue 2, Pages 133-135Publisher
INT RESEARCH & COOPERATION ASSOC BIO & SOCIO-SCIENCES ADVANCEMENT
DOI: 10.5582/ddt.2015.01026
Keywords
Animal model; silkworm; drug discovery
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Funding
- Grants-in-Aid for Scientific Research [26460062] Funding Source: KAKEN
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We advocate the use of silkworm larvae, Bombyx mori, as an animal model for discovery of drug candidates. We have established several disease models using silkworms, which offer technical advantages in drug development and the study of host-pathogen interaction. This mini review briefly describes recent trends in the use of silkworm larvae as a non-mammalian model for drug discovery and it offers suggestions regarding the potential for silkworm use in pharmaceutical-biomedical research.
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