Journal
GASTROENTEROLOGY
Volume 154, Issue 2, Pages 289-301Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.gastro.2017.07.040
Keywords
GERD; Mucosal Impedance; Reflux Monitoring
Categories
Funding
- Sandhill Scientific Inc. (Denver, Colorado)
- Sandhill Scientific (Denver, Colorado)
- Reckitt Benckiser (Hull, UK)
Ask authors/readers for more resources
A detailed critique of objective measurements of gastroesophageal reflux disease (GERD) would improve management of patients suspecting of having reflux, leading to rational selection of treatment and better outcomes. Many diagnostic tests for GERD have been developed over the past decades. We analyze their development, positive- and negative-predictive values, and ability to predict response to treatment. These features are important for development of medical, surgical, and endoscopic therapies for GERD. We discuss the value of available diagnostic tests and review their role in management of patients with persistent reflux symptoms despite adequate medical or surgical treatment. This is becoming a significant health economic problem, due to the widespread use of proton pump inhibitors. GERD is believed to cause nonesophageal symptoms, such as those provoked by ear, nose, throat, or respiratory disorders. We analyze the value of GERD diagnostic tests in evaluation of these troublesome, nonesophageal symptoms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available