Journal
GASTROENTEROLOGIA Y HEPATOLOGIA
Volume 41, Issue 8, Pages 514-529Publisher
ELSEVIER ESPANA SLU
DOI: 10.1016/j.gastrohep.2018.05.029
Keywords
Calprotectin; Crohn's disease; Ulcerative colitis; Endoscopic remission; Histological remission; Postsurgical recurrence
Categories
Ask authors/readers for more resources
The management of inflammatory bowel disease (IBD) is currently based on the objective evaluation of intestinal lesions. It would therefore be interesting to have access to simple and non-invasive tools to monitor IBD activity and to identify the presence of lesions. Faecal calprotectin (FC) is the main cytosolic protein of neutrophils, it is resistant to bacterial degradation and it is stable at room temperature for several days, characteristics that make it suitable for use in clinical practice. It can be used to differentiate between inflammatory and functional processes, it correlates with endoscopic activity, it is associated with clinical and endoscopic response to treatment and it has short-term prognostic value. This paper offers an up-to-date perspective on the information that FC can provide clinicians to aid diagnosis, monitoring and management of IBD. (C) 2018 The Author(s). Published by Elsevier Espana, S.L.U.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available