Journal
FEMS MICROBIOLOGY REVIEWS
Volume 39, Issue 3, Pages 392-412Publisher
OXFORD UNIV PRESS
DOI: 10.1093/femsre/fuv011
Keywords
RNA helicase; ribosome biogenesis; translation initiation; RNA turnover; bacteria; gene expression
Categories
Funding
- Swiss National Science Foundation
- canton of Geneva
- Boninchi foundation
- E & L Schmidheiny foundation
- Novartis Consumer Health Foundation
- Swiss Life
- Novartis Jubilaums foundation
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RNA helicases of the DEAD-box and DEAH-box families are important players in many processes involving RNA molecules. These proteins can modify RNA secondary structures or intermolecular RNA interactions and modulate RNA-protein complexes. In bacteria, they are known to be involved in ribosome biogenesis, RNA turnover and translation initiation. They thereby play an important role in the adaptation of bacteria to changing environments and to respond to stress conditions.
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