Journal
FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 23, Issue -, Pages 36-42Publisher
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/4580
Keywords
Bacterial Infections; Antibiotic Resistance; RecA; Drug Targets
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The spread of bacterial infectious diseases due to the development of resistance to antibiotic drugs in pathogenic bacteria is an emerging global concern. Therefore, the efficacious management and prevention of bacterial infections are major public health challenges. RecA is a pleiotropic recombinase protein that has been demonstrated to be implicated strongly in the bacterial drug resistance, survival and pathogenicity. In this minireview, RecA's role in the development of antibiotic resistance and its potential as an antimicrobial drug target are discussed.
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