Journal
FUTURE MEDICINAL CHEMISTRY
Volume 7, Issue 8, Pages 975-978Publisher
FUTURE SCI LTD
DOI: 10.4155/FMC.15.50
Keywords
cellular thermal shift assay; CETSA; phenotypic-based drug-discovery; R&D efficiency; target engagement; target-based drug-discovery
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CETSA shows great promise as an indispensable tool in drug discovery enabling the critical demonstration of target engagement in primary human cells and potentially also patient cells.
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