Journal
FOOD CHEMISTRY
Volume 240, Issue -, Pages 16-23Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2017.07.072
Keywords
Antibiotics; Clam; HPLC-MS/MS; Mussel
Funding
- Ph.D. fellowship in Veterinary and Animal Science in the Laboratory of Inspection of Food of Animal Origin at the University of Milan
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Filter feeders, like mussels and clams, are suitable bioindicators of environmental pollution. These shellfish, when destined for human consumption, undergo a depuration step that aims to nullify their pathogenic microorganism load and decrease chemical contamination. Nevertheless, the lack of contamination by drugs may not be guaranteed. Antimicrobials are a class of drugs of particular concern due to the increasing phenomenon of antibiotic resistance. Their use in breeding and aquaculture is a major cause of this. We developed a multiclass method for the HPLC-MS/MS analysis of 29 antimicrobials, validated according to the Commission Decision 2002/657/UE guidelines, and applied it to 50 mussel and 50 clam samples derived from various Food and Agricultural Organisation marine zones. The results obtained, indicate a negligible presence of antibiotics. Just one clam sample showed the presence of oxytetracycline at a concentration slightly higher than the European Union Maximum residue limit set for fish. (C) 2017 Published by Elsevier Ltd.
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