Journal
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume 36, Issue 4, Pages 1130-1137Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/bkcs.10210
Keywords
Adsorption; Bovine serum albumin; Protein; Monodisperse polymers; HPMA-Cl-co-EGDMA particles
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A novel adsorbent has been synthesized by functionalization of monodisperse porous poly(3-chloro-2-hydroxypropyl methacrylate-co-ethylene glycol dimethacrylate) particles with phenylalanine (Phe) as a protein-selective ligand. The polymer particle can adsorb protein in its isoelectric pH (4.8), and its maximum capacity is ca. 633 mg/g. The adsorption behavior of poly(HPMA-Cl-co-EGDMA) with Phe resin obeyed Langmuir isotherm well.
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