Journal
FITOTERAPIA
Volume 125, Issue -, Pages 89-93Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2017.12.005
Keywords
Phyllanthus acidus; Phyllanthaceae; Cleistanthane diterpenoids; Phyllaciduloids A-D
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Funding
- National Natural Science Foundation of China [81611130132, 81473121]
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Four new cleistanthane diterpenoids, phyllaciduloids A-D (1-4), were isolated from the roots and stems of Phyllanthus acidus (L.) Skeels (Phyllanthaceae). Their structures were elucidated on the basis of extensive spectroscopic analysis. Phyllaciduloids B-D (2-4) present in their structures with ether bond between C-7 and C-16, which were rarely reported. All the isolates were evaluated for their cytotoxic activities against five human cancer cell lines.
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