4.6 Review

Canonical signaling and nuclear activity of mTORa teamwork effort to regulate metabolism and cell growth

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis

Wei Wan et al.

MOLECULAR CELL (2017)

Article Cell Biology

Multistep regulation of TFEB by MTORC1

Silvia Vega-Rubin-de-Celis et al.

AUTOPHAGY (2017)

Article Biochemistry & Molecular Biology

Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling

Gina Lee et al.

Review Cell Biology

mTORC1 signaling and the metabolic control of cell growth

Issam Ben-Sahra et al.

CURRENT OPINION IN CELL BIOLOGY (2017)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth, Metabolism, and Disease

Robert A. Saxton et al.

Review Biochemistry & Molecular Biology

Nutrient sensing and TOR signaling in yeast and mammals

Asier Gonzalez et al.

EMBO JOURNAL (2017)

Article Biochemistry & Molecular Biology

mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation

A. Alayev et al.

ONCOGENE (2016)

Article Cell Biology

mTOR signaling regulates myotube hypertrophy by modulating protein synthesis, rDNA transcription, and chromatin remodeling

Ferdinand von Walden et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)

Review Cell Biology

The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging

Brian K. Kennedy et al.

CELL METABOLISM (2016)

Review Cell Biology

Amino Acid Sensing bymTORC1: Intracellular Transporters Mark the Spot

Deborah C. I. Goberdhan et al.

CELL METABOLISM (2016)

Correction Cell Biology

ATM and ATR signaling at a glance (vol 128, pg 4255, 2015)

Poorwa Awasthi et al.

JOURNAL OF CELL SCIENCE (2016)

Article Multidisciplinary Sciences

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

Issam Ben-Sahra et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer

Genevieve Deblois et al.

NATURE COMMUNICATIONS (2016)

Article Physiology

Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR)

Joan M. Boylan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2015)

Article Multidisciplinary Sciences

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1

Jinbo Han et al.

NATURE (2015)

Article Genetics & Heredity

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

Mark M. Pomerantz et al.

NATURE GENETICS (2015)

Review Cell Biology

Regulation of mTORC1 by PI3K signaling

Christian C. Dibble et al.

TRENDS IN CELL BIOLOGY (2015)

Article Cell Biology

Dynamic Visualization of mTORC1 Activity in Living Cells

Xin Zhou et al.

CELL REPORTS (2015)

Review Chemistry, Multidisciplinary

The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases

Etienne Audet-Walsh et al.

ACTA PHARMACOLOGICA SINICA (2015)

Review Cell Biology

Rapamycin: One Drug, Many Effects

Jing Li et al.

CELL METABOLISM (2014)

Article Multidisciplinary Sciences

Coordinated regulation of protein synthesis and degradation by mTORC1

Yinan Zhang et al.

NATURE (2014)

Review Cell Biology

Making new contacts: the mTOR network in metabolism and signalling crosstalk

Mitsugu Shimobayashi et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

A Year in Structural Signaling: mTOR-The PIKK of the Bunch?

Stephen J. Smerdon

SCIENCE SIGNALING (2014)

Review Cell Biology

mTORC1 signaling controls multiple steps in ribosome biogenesis

Valentina Iadevaia et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)

Review Oncology

Beyond DNA Repair: DNA-PK Function in Cancer

Jonathan F. Goodwin et al.

CANCER DISCOVERY (2014)

Review Biochemistry & Molecular Biology

Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)

Anna R. Malik et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)

Review Cell Biology

A Central Role for mTOR in Lipid Homeostasis

Dudley W. Lamming et al.

CELL METABOLISM (2013)

Review Cell Biology

Where is mTOR and what is it doing there?

Charles Betz et al.

JOURNAL OF CELL BIOLOGY (2013)

Article Cell Biology

Regulation of mTORC1 and its impact on gene expression at a glance

Mathieu Laplante et al.

JOURNAL OF CELL SCIENCE (2013)

Article Multidisciplinary Sciences

Glucose-TOR signalling reprograms the transcriptome and activates meristems

Yan Xiong et al.

NATURE (2013)

Review Oncology

Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond

Genevieve Deblois et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis

Valentina Iadevaia et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2012)

Article Biochemistry & Molecular Biology

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Carmine Settembre et al.

EMBO JOURNAL (2012)

Article Biochemistry & Molecular Biology

Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target of rapamycin

M. Carmen Ortells et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Multidisciplinary Sciences

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

Joshua L. Owen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

Agnes Roczniak-Ferguson et al.

SCIENCE SIGNALING (2012)

Article Cardiac & Cardiovascular Systems

Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium

Rebecca K. Harston et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Article Biochemistry & Molecular Biology

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

Timothy R. Peterson et al.

Letter Cell Biology

mTOR protein localization is cell cycle regulated

Margit Rosner et al.

CELL CYCLE (2011)

Article Biochemistry & Molecular Biology

Regulation of TFEB and V-ATPases by mTORC1

Samuel Pena-Llopis et al.

EMBO JOURNAL (2011)

Review Cell Biology

Pioneer transcription factors: establishing competence for gene expression

Kenneth S. Zaret et al.

GENES & DEVELOPMENT (2011)

Review Cell Biology

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile

Beatrice T. Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes

Chi Kwan Tsang et al.

CELL CYCLE (2010)

Article Medicine, Research & Experimental

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

Jianhui Ma et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

mTORC1 Directly Phosphorylates and Regulates Human MAF1

Annemieke A. Michels et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

Katrin Duevel et al.

MOLECULAR CELL (2010)

Article Multidisciplinary Sciences

mTORC1 controls fasting-induced ketogenesis and its modulation by ageing

Shomit Sengupta et al.

NATURE (2010)

Article Multidisciplinary Sciences

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Shijie Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

Theodoros Kantidakis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Pharmacology & Pharmacy

Rapamycin Down-Regulates Inducible Nitric Oxide Synthase by Inducing Proteasomal Degradation

Hye Kyoung Jin et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)

Article Biochemistry & Molecular Biology

Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

Yuehua Wei et al.

EMBO JOURNAL (2009)

Article Cell Biology

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

Thomas Porstmann et al.

CELL METABOLISM (2008)

Review Endocrinology & Metabolism

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

Vincent Giguere

ENDOCRINE REVIEWS (2008)

Article Biochemistry & Molecular Biology

PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex

Annette Woiwode et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Integration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4

Teddy T. C. Yang et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Review Endocrinology & Metabolism

ERR alpha: a metabolic function for the oldest orphan

Josep A. Villena et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway

Jeong-Ho Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex

John T. Cunningham et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

Stephen C. Land et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Oncology

Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells

Pilar Garcia-Morales et al.

MOLECULAR CANCER THERAPEUTICS (2006)

Article Multidisciplinary Sciences

PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR

Rosa Bernardi et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Functional Genomics identifies TOR-regulated genes that control growth and division

David A. Guertin et al.

CURRENT BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

DD Sarbassov et al.

MOLECULAR CELL (2006)

Article Cell Biology

mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators

GA Nader et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)

Article Multidisciplinary Sciences

Location analysis of estrogen receptor α target promoters reveals that FOXA1 defines a domain of the estrogen response

J Laganière et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Central role of Ifh1p-Fhl1p interaction in the synthesis of yeast ribosomal proteins

D Rudra et al.

EMBO JOURNAL (2005)

Article Multidisciplinary Sciences

Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression

RM Marion et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock

T Preiss et al.

NATURE STRUCTURAL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin

CC Hudson et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture

XW Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

JE Kim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)