Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 46, Issue 3, Pages 188-194Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000155
Keywords
aging; force; sarcopenia; neuromuscular control; fiber type; cross-sectional area
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Funding
- National Heart, Lung, and Blood Institute at the National Institute of Health [PO1 HL1091830]
- Veteran's Administration Rehabilitation Research and Development Service [E6910-R, E1697-R, E9275-L, E1433-P]
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Although skeletal muscle function is diminished with advanced age, single muscle fiber function seems to be preserved. Therefore, this review examines the hypothesis that the skeletal muscle fiber, per se, is not the predominant factor responsible for the reduction in force-generating capacity in the oldest-old, but, rather, is attributable to a combination of factors external to the muscle fibers.
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